Health Articles

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What is N-acetylcysteine

N-acetylcysteine, also known as Acetylcysteine, NAC or N-acetyl-cysteine, is a derivative of an amino acid called cysteine which is important in the production of glutathione, a potent antioxidant in human body.

Benefits of N-acetylcysteine

  1. Antioxidative function

When consumed, N-acetylcysteine gets converted into L-cysteine, an amino acid that is the direct precursor to glutathione in human body. Glutathione is a potent antioxidant that can neutralize free radicals and thus protect your body cells and tissues from oxidative damage.1 Therefore, N-acetylcysteine acts as an antioxidant by replenishing the glutathione pool in body cells that becomes depleted with increased level of inflammation and oxidative stress in human body.2 This antioxidant property can help improve illnesses caused by oxidative stress, such as heart disease and infertility as well as help maintaining healthy function of immune system.3, 4, 5

2. Liver-protective function

N-acetylcysteine has been used for long as the mainstay treatment and antidote for paracetamol overdose to prevent or reduce liver damage.6 When given intravenously within 8 hours after the ingestion of paracetamol, the treatment is highly effective.6 N-acetylcysteine is also found to improve liver function in patients with non-paracetamol induced liver failure and non-alcoholic fatty liver disease thanks to its antioxidative and anti-inflammatory effect.7, 8

3. Helps relieve symptoms of respiratory condition

N-acetylcysteine is also commonly used to reduce phlegm in respiratory system. It achieves this effect by acting as mucolytic agent that reduces mucus viscosity and as a muco-regulatory agent which reduces airway mucus secretion.2 These effects, along with the anti-inflammatory and antioxidant properties of N-acetylcysteine helps to improve breathing and lung function in lung disorders such as chronic obstructive pulmonary disease, chronic bronchitis and many others.2, 9

4. Kidney-protective function

N-acetylcysteine has been speculated to be able to slow down the progress of chronic kidney disease by reducing serum creatinine and improving the structure of some of the cells in kidneys.10, 11

5. May improve mental health condition and substance use disorder

In recent years, there has been increasing interest in the use of N-acetylcysteine in helping to manage mental health conditions and substance use disorder. N-acetylcysteine has been discovered to be able to regulate the level of glutamate, an important neurotransmitter in human brain. 12 While glutamate is needed for normal brain activity, excess glutamate in brain has been found to be associated with mental illnesses such as schizophrenia or depression. 13, 14 When used in patient with substance use disorders, especially to treat young individuals addicted to cocaine and cannabis, N-acetylcysteine is effective in reducing the craving for the substances and can help abstinent individuals to prevent relapsing.13 There are also promising evidence for the use of N-acetylcysteine in treating obsessive-compulsive disorders and mood disorders, but better designed studies are required to further investigate its clinical effectiveness. 13

6. May improve fertility

N-acetylcysteine has been yielding positive results in studies that look into fertility improvement in recent years. It was found that N-acetylcysteine can be helpful in polycystic ovarian syndrome(PCOS)-related and unexplained female infertility, especially in women with high BMI, insulin resistance, and oxidative stress15 N-acetylcysteine is also discovered to have ovulation induction properties and thus can be an effective adjuvant to improves pregnancy rate in patients receiving intrauterine insemination.16 However, more well-controlled studies still need to be done to further confirm and establish the findings.

Risks and side effects of N-acetylcysteine

N-acetylcysteine on its own has very good tolerability and safety profile even at high dose.8, 13, 14 The most common side effects that are associated with it are mainly gastrointestinal disorders such as diarrhea, gastric reflux, bloating. 14, 17

However, N-acetylcysteine can potentiate the vasodilation effect of Nitroglycerin, an antianginal medication which can lead to higher incidence of side effects such as headache and severe hypotension.18, 19

People who are taking blood thinning medication, have bleeding disorders or for those who are about to undergo major surgery also need to be cautious with the use of N-acetylcysteine because N-acetylcysteine has anticoagulant and platelet-inhibiting properties, thus can increase bleeding risk.20

References

  1. Ershad M, Naji A, Vearrie D. National Center for Biotechnology Information [Internet]. N Acetylcysteine. National Library of Medicine; 2023 [cited 2023Apr22]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537183/
  2. Sadowska AM. N-Acetylcysteine mucolysis in the management of chronic obstructive pulmonary disease. Therapeutic Advances in Respiratory Disease. 2012;6(3):127-135. 
  3. Shackebaei D, King N, Shukla B, Suleiman MS. Mechanisms underlying the cardioprotective effect of L-cysteine. Mol Cell Biochem. 2005;277(1-2):27-31.
  4. Adeoye O, Olawumi J, Opeyemi A, Christiania O. Review on the role of glutathione on oxidative stress and infertility. JBRA Assist Reprod. 2018;22(1):61-66.
  5. Dröge W, Breitkreutz R. Glutathione and immune function. Proc Nutr Soc. 2000;59(4):595-600.
  6. Daly, F. F., Fountain, J. S., Murray, L., Graudins, A., & Buckley, N. A. (2008). Guidelines for the management of paracetamol poisoning in Australia and New Zealand-explanation and elaboration. Medical journal of Australia188(5), 296.
  7. Dludla PV, Nkambule BB, Mazibuko-Mbeje SE, et al. N-Acetyl Cysteine Targets Hepatic Lipid Accumulation to Curb Oxidative Stress and Inflammation in NAFLD: A Comprehensive Analysis of the Literature. Antioxidants (Basel). 2020;9(12):1283. Published 2020 Dec 16.
  8. Nabi T, Nabi S, Rafiq N, Shah A. Role of N-acetylcysteine treatment in non-acetaminophen-induced acute liver failure: A prospective study. Saudi J Gastroenterol. 2017;23(3):169-175.
  9. Cazzola M, Calzetta L, Page C, et al. Influence of N-acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis. Eur Respir Rev. 2015;24(137):451-461.
  10. Tian N, Rose R, Jordan S, Dwyer TM, Hughson MD, Manning RD Jr. N-acetylcysteine improves renal dysfunction, ameliorates kidney damage and decreases blood pressure in salt-sensitive hypertension. J Hypertens. 2006;24:2263–2270.
  11. Ye M, Lin W, Zheng J, Lin S. N-acetylcysteine for chronic kidney disease: a systematic review and meta-analysis. Am J Transl Res. 2021;13(4):2472-2485.
  12. Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neuroscience. 2nd edition. Sunderland (MA): Sinauer Associates; 2001. Glutamate. Available from: https://www.ncbi.nlm.nih.gov/books/NBK10807/
  13. McQueen G, Lally J, Collier T, et al. Effects of N-acetylcysteine on brain glutamate levels and resting perfusion in schizophrenia. Psychopharmacology (Berl). 2018;235(10):3045-3054. doi:10.1007/s00213-018-4997-2
  14. Onaolapo AY, Onaolapo OJ. Glutamate and depression: Reflecting a deepening knowledge of the gut and brain effects of a ubiquitous molecule. World J Psychiatry. 2021;11(7):297-315.
  15. Devi N, Boya C, Chhabra M, Bansal D. N-acetyl-cysteine as adjuvant therapy in female infertility: a systematic review and meta-analysis. J Basic Clin Physiol Pharmacol. 2020;32(5):899-910.
  16. Bedaiwy, M.A., RezkH. Al Inany, A. and Falcone, T. (2004) “N-acetyl Cystein improves pregnancy rate in long standing unexplained infertility: A novel mechanism of ovulation induction,” Fertility and Sterility, 82.
  17. Calverley P, Rogliani P, Papi A. Safety of N-Acetylcysteine at High Doses in Chronic Respiratory Diseases: A Review. Drug Saf. 2021;44(3):273-290.
  18. Horowitz JD, Henry CA, Syrjanen ML, et al. Nitroglycerine/N-acetylcysteine in the management of unstable angina pectoris. Eur Heart J. 1988;9 Suppl A:95-100.
  19. Ardissino D, Merlini PA, Savonitto S, et al. Effect of transdermal nitroglycerin or N-acetylcysteine, or both, in the long-term treatment of unstable angina pectoris. J Am Coll Cardiol. 1997;29(5):941-947.
  20. Niemi TT, Munsterhjelm E, Pöyhiä R, Hynninen MS, Salmenperä MT. The effect of N-acetylcysteine on blood coagulation and platelet function in patients undergoing open repair of abdominal aortic aneurysm. Blood Coagul Fibrinolysis. 2006;17(1):29-34.


Hair Loss

It’s normal to lose between 50- 100 hairs a day. You may experience losing more hair than is normal if you notice a large amount of hair in the drain after washing your hair or clumps of hair in your brush.
If you notice that you are losing more hair than usual, you should discuss the problem with doctor or pharmacist. They can suggest appropriate treatment plan.

What causes hair loss?

  1. Hormonal Changes
    • Pregnancy
    • Childbirth
    • Menopause
  2. Medical Conditions
    • Thyroid disease
    • Scalp infections like ringworm
    • Medication used to treat cancer
  3. Stress
  4. Family history (heredity)
  5. Nutrition Deficiency
  6. Effect of certain hair styles (wearing tight ponytail and braids)

In men, the typical pattern of hair loss is a receding hair line with loss of hair from the top and front of the head, often in a classic M-shaped pattern. In women, the usual pattern of hair loss is thinning at the crown of the head, with the frontal hairline over the forehead remaining.
Androgenetic Alopecia is caused by both genetic and hormonal factors. This form of hair loss is related to hormones called androgens, particularly an androgen called dihydrotestosterone (DHT). Increased levels of androgens such as DHT in hair follicles can lead to a shorter cycle of hair growth and the growth of shorter and thinner strands of hair. Follicles can also stay in the resting phase for longer periods of time.

Traction Alopecia is a type of hair loss caused by constant pulling. The commonest cause is tight hairstyles such as braids or a ponytail. It can also occur from using chemical relaxers or even hair extensions. Traction Alopecia is not usually permanent, especially if it is diagnosed early. Often, recognizing the problem and avoiding putting strain on the hair will allow full regrowth. If Traction Alopecia is diagnosed too late, the hair follicles may have been destroyed and hair will not regrow.

Management of Hair Loss

MEDICATION

  • Finasteride (Propecia) is used in male-pattern hair loss in a pill form, taken 1 milligram per day. It is not indicated for women and pregnant women.
  • Minoxidil (Rogaine or Regro) is available OTC and applied twice daily to the scalp, eyebrows, and beard.
  • Dutasteride is another oral medication that works similarly to finasteride.

MULTIVITAMIN FOR HAIR LOSS

  • Vitamins A, B, E
    All are important to the hair growth and retention processes.
  • Biotin
    Studies suggest that including biotin-rich food in your diet or taking biotin supplement may slow hair loss such as nuts, sweet potatoes, eggs, onions and oats in your diet.
  • Iron, Folic Acid, Zinc
    Healthy hair needs these to keep growing thick and strong.

HAIR CARE

  • Anti-thinning shampoo
    Shampoo for hair loss contain vitamins and amino acids that provide healthier scalp to generate more hair over time. You can also ask your doctor/pharmacist about the right selection of shampoo.
  • Scalp massage
    When you wash your hair, gently apply pressure with your fingertips (not finger nails) around your scalp to increase blood flow, resulting in hair re-growth.
  • Gentle styling
    Skip tight braids or ponytails that may pull on hair at the root and lead to hair loss. Must always dry your hair before styling to avoid irritating scalp.
  • Avoid constant heating and drying
    Heat weakens hair proteins, and constant heating and drying can lead to weakness and fragility that causes hair loss.
  • Keep away from chemicals
    Harsh chemicals and permanent hair colour products could be damaging for hair health.

NATURAL REMEDIES

  • Onion juice
    Onion juice helps in blood circulation and promoting hair growth. Apply the juice to your scalp and hair and leave in for at least 15 minutes or leave it overnight and wash it normally. Do it regularly for a week and you will see noticeable result.
  • Coconut oil 
    Coconut oil contains fatty acids that penetrate inside the hair shaft and reduce protein loss from hair. Coconut oil can be used either before or after you wash your hair depending on your hair type. If your hair tends to be oily, you can do a leave-in treatment overnight or for a few hours before you wash it. Massage it into your scalp and all of your hair. If your hair is dry, you can also use it as a leave-in treatment.

If you want to improve your hair, come up with a plan and stay consistent. Remember that the treatments may take a few months to yield noticeable results.
It’s important that you take time each day to focus on nourishing your hair to get the luscious locks you want. Taking this step and practicing self-care will be extra beneficial if your hair loss is related to any emotional or stress-related issue.
Stay positive and do your best to maintain a healthy lifestyle that will complement your hair treatment plan.

Allergic Rhinitis

Allergic rhinitis is an inflammatory condition that affects the nasal passages, sinuses, ears, and throat. It occurs when the immune system overreacts to the allergens in the surroundings.
There are two types of allergic rhinitis. Seasonal allergy sufferers develop symptoms during spring, fall, or both seasons when they become exposed to airborne pollen and outdoor mold spores. Perennial allergic rhinitis, which is year-around, is caused by indoor allergens such as house dust, pet dander, dust mites, and indoor molds.

DIFFERENCES OF ALLERGIC RHINITIS, COLD, FLU AND COVID

                           


Allergic Rhinitis is always triggered by breathing in the tiny particles of allergens. The common allergens that causes are pollens, dust, smoke, moulds and flakes of animal skins.

SYMPTOMS OF ALLERGIC RHINITIS


The common symptoms of having Allergic Rhinitis includes sneezing, stuffy or runny nose. Sometimes, the eyes also get red, itchy and watery. Swelling of eyes also happen occasionally.

TREATMENT OF ALLERGIC RHINITIS

You can treat your allergic rhinitis in several ways. These include medications, as well as home remedies and possibly alternative medicines.

MEDICATION

Antihistamine

You can take antihistamines to treat allergies. They work by stopping your body from making histamine.

Examples of antihistamine:
– Chlorpheniramine (Piriton)
– Cetirizine (Zyrtec)
– Loratadine (Clarityne)
– Fexofenadine (Telfast)
– Desloratadine (Aerius)
– Levocetirizine (Xyzal)

Nasal Decongestant Spray (Iliadin, Afrin, Oxy-Nase)

This medication is used for temporary relief of congestion in the nose. It works by narrowing the blood vessels in the nose area, reducing swelling and nose blockage.
Do not use more often, use more sprays, or use longer than directed because doing so may increase the risk of side effects. Also, DO NOT use this medication for more than 10 days. If you use it for longer than the recommended period of time, your congestion/nose blocking may get worsen.

Instructions to use Nasal Spray

ALTERNATIVE AND COMPLEMENTARY MEDICINE

Saline Nasal Irrigation

You can do this by using a solution made with sachets bought from a pharmacy such as Neilmed, EMS, Marimer, Sterimar etc.
Nasal irrigation can be carried out as often as necessary, but a fresh solution should be made each time.

Eucalyptus or Menthol Steam Inhalation

Eucalyptus oil extracted from the leaves of the eucalyptus tree, has anti-inflammatory and antibacterial properties.

Using steam to open the passages in the nose can help to relieve sinus pressure. Steam inhalation is easy to do at home. Boil water, pour it into a large bowl, add in some eucalyptus oil or menthol and lean over, so the face is directly above the water. Cover the head with a towel, and breathe through the nose.

Probiotics & Prebiotics

Probiotics are microorganisms that might offer health benefits by helping the body maintain a healthful balance of gut bacteria.
Probiotics may boost a person’s immune system, which can help the body fight off allergies.
Probiotics also increase good bacteria in your gut, which is thought to help regulate allergy cells throughout the body.
Prebiotics are non-digestible oligosaccharides that encourage the growth of probiotic bacteria.

Vitamin C

Increasing your intake of vitamin C can help alleviate your symptoms because this antioxidant counteracts histamine, the substance that can contribute to inflammation, runny nose, sneezing, and other related symptoms.

Omega-3 fatty acids

Because omega-3 fatty acids are essential fats with anti-inflammatory properties, increasing the consumption of these healthy fats can reduce immune dysfunction and help alleviate allergy-related conditions.

Acne Management


By Ms Lew Hui Li & Ms Chong Hui Ying

Acne or acne vulgaris is a skin condition that occurs when a pore get clogged with dead skin cells, oils and a type of bacteria called Propionibacterium acnes (P. acnes). Acne is triggered by many factors:

  • Hormones
  • Stress
  • Poor hygiene
  • Wrong skin care products
  • Sun
  • Unhealthy diet


Non Inflammatory Acne Types (Less severe)

Usually do not cause swelling and are not painful.
Examples: Whiteheads/Close comedones; Blackheads/Open comedones

Inflammatory Acne Types (More severe)

It is more likely to cause complications such as scarring or pitting.
Examples: Papules; Pustules; Nodules; Cysts

Treatment- Mild Acne

Mild acne can be treated with over-the-counter (OTC) medications, such as gels, soaps, pads, creams, and lotions, that are applied to the skin. OTC acne remedies may contain the following active ingredients:

  • Resorcinol: helps break down blackheads and whiteheads
  • Benzoyl peroxide: kills bacteria, accelerates the replacement of skin, and slows the production of sebum
  • Salicylic acid: assists the breakdown of blackheads and whiteheads and helps reduce inflammation and swelling.
  • Retin-A: helps unblock pores through cell turnover
  • Azelaic acid: strengthens cells that line the follicles, stops sebum eruptions, and reduce bacteria growth.

Treatment- Moderate Acne

A skin specialist, or dermatologist, can treat more severe cases.

  • Corticosteroid injection: help prevent scarring, reduce inflammation, and speed up healing.
  • Oral antibiotics: combat the growth of bacteria and reduce inflammation, erythromycin and tetracycline are commonly prescribed for acne
  • Oral contraceptives: help control acne in women by suppressing the overactive gland.
  • Topical antimicrobials:  reduce P. acnes  (example: clindamycin)
  • Retinoic acid derivatives: unclog pores and prevent whitehead and blackhead from developing (example: adapalene, tretinoin)

Prevention and Management Tips

DO

STAY HYDRATED
This doesn’t just mean drink a lot of water. Must use a suitable moisturizer to keep skin hydrated.

KEEP GOOD HYGIENE
Wash your pillow cases and clean spectacles regularly as they collect sebum and skin residues. Also must wash hands before
touching your face.

TAKE HIGH FIBER FOOD
Green leafy vegetables, nuts, fish rich in omega 3 fatty acids are helpful in acne.

USE SUNSCREEN
Sun, heat and humidity can cause oil glands to be overactive which lead to breakouts. Must choose oil free non-comedogenic
physical sunscreens.

CONSULT A DERMATOLOGIST OR PHARMACIST
Expertise of medical professionals can help to uncover source of acne and develop a treatment plan that best suitable for you.



DON’T

NEGLET YOUR HEALTH
Maintaining good mental and physical health always contribute to more healthier skin.

OVER CLEANSE
Wash your face not more than twice each day by using mild soap. Over-cleanse it or using facial cleanser with strong cleansing
effect will strip your face.

TAKE HIGH GLYCEMIC INDEX DIET
Food rich in sugar, carbohydrate and milk is known to increase acne.

PICK, POKE OR POP
This will increase the risk of infections, scarring and make your acne take longer to heal.

DITCH MEDICATION TOO SOON
It can takes up to 8 weeks before some prescribed medication has an effect on your acne. Therefore it’s important to resist the urge
of quit the medication too soon.

Constipation


Constipation is a very common problem people facing nowadays. So, what is constipation?
Medically speaking, constipation is when you have infrequent or hard to pass bowel movements (meaning they are painful and stools hard to pass) and have a feeling that you have not fully emptied your bowels. Infrequent in this case means less than three times per week. Most of the time, constipation can be treated but if there is ongoing pain with bowel movements or there is blood in stool, seek medical assistance instead.


What causes Constipation?

Common Lifestyle

  • Eating foods low in fiber can make the stools become hard and difficult to pass.
  • Changes in diet or daily routine especially when travelling along with inactivity
  • Dehydration can worsen constipation, making the stool dry or like small lumps.
  • Lack of exercise
  • Often ignoring the urge to go to toilet due to too busy or doesn’t want to use the public toilet and as the feeling goes off , constipation occur
  • Stress as when a person stressed, he/she is more likely to have an unhealthy diet, not getting enough exercise/sleep or forget to stay hydrated.

Medications and Health Condition

  • Medicine like pain medications (mainly opioids), high calcium antacid and iron pills can cause constipation.
  • Lazy Bowel Syndrome which the colon contracts poorly and restrains stool. ( due to excessive usage of stimulant laxative)
  • Pregnancy

Treatment of Constipation

Lifestyle changes to treat constipation

Diet

  • Eat a well-balanced diet with whole grains, fresh fruits and veggies. Aim for at least least 3 servings of vegetables and at least 2 servings of fruit per day. A serve is a portion equivalent in size of your own fist.
  • Eat fewer high fat foods such as meat, eggs, cheese and processed foods.
  • Add fiber supplements to your diet if needed. But remember to drink plenty of water because water help fiber work more efficiently.
  • Drink at least 8 glasses of water per day.
  • Avoid caffeine-containing drinks and alcohol, which can cause dehydration.

Habit

  • Don’t ignore the urge to pass motion. The longer you wait, the harder your stool can become.
  • Check how you sit on the toilet. Raising your feet, leaning back or squatting may make having a bowel movement easier.
  • Exercise regularly to prevent or treat constipation by lowering the time it takes for food to move through large intestine. Hence less water will be absorbed from the stool into body.
  • Do not read, use your phone or other devices while trying to move your bowels.

Supplements

Probiotics

Probiotics can play a key role in helping to relieve constipation, but it can be confusing trying to choose the correct and most effective one. Here we aim to help you get the most out of your friendly bacteria.
Bifidobacteria and Lactobacillus species are the majority bacteria found in our large intestine, hence probiotics with specific strains belonging to these species are regarded as the most suitable in helping to relieve constipation.
Megalive Floramax Pro, Megalive Flora 60 Plus, Bio-life A.B Junior Pre&Probiotics, Hexbio etc are probiotics supplements containing those strains which can be found in the market. Generally, probiotic food and supplements are thought to be safe for most people including during pregnancy and breastfeeding. Talk to your doctor or pharmacist, choosing the most suitable probiotics for you and your family, turning unhappy tummies to happy ones.

Over-the-counter Option

There are a number of options to help treat constipation despite to the lifestyle changes. They can be found over-the-counter without a prescription and come in many forms like pills, powders (to mix with water), enemas or suppositories. Talk with your pharmacist to help you choose wisely.

Bulk-Forming Laxative

Bulk-forming laxatives work by absorb liquid in the intestine. This creates a bulky, more liquid like stool which in turn stimulates your bowel.
Bulk-forming laxatives often use as first line of treatment before start using stimulant laxative.

Take note:

  • It takes up to 2 to 3 days to works.
  • Increased water intake when taking bulk forming agent or else may back up and block your bowel.
  • Some people may experience mild stomach pain, bloating or gas.

Examples of agents: Psyllium husk, Bran, Isphagula husk (Fybrogel)

Osmotic Laxative

Osmotic laxatives draw water from the rest of the body into your bowel to soften poo and make it easier to pass.

Take note:

  • It takes up to 1 to 2 days to works.
  • The most common side effects are stomach pain, diarrhea, bloating or gas.
  • Cautious in elderly and people with heart or kidney failure. Talk to your doctor or pharmacist before taking it.

Examples of agents: Lactulose (Lactul), Macrogol (Forlax)

Stimulant Laxative

Stimulant laxatives trigger the intestine to contract and push out the stool.

Take note:

  • It takes up to 6 to 8 hours to works.
  • Do not use stimulant laxative for more than a week as overuse it may cause lazy intestine.
  • Do not use for pregnant mother as it can cause contraction of uterus.

Examples of agents: Bisacodyl (Dulcolax), Senna (Senokot)

Stool Softener

Stool softener are used on short term basis to relieve constipation for people who should avoid straining during bowel movements such as hemorrhoids, heart disease, after surgery and other conditions.
They works by letting water into stool to soften it and make it easier to pass.

Examples of agents: Docusate NA

Diabetes – What should I eat?

 

Living with diabetes does not have to mean feeling deprived. People can learn to balance meals and make healthy food choices while still including the foods they enjoy. Both sugary and starchy carbohydrates can raise blood sugar levels, but people can choose to include these foods in the right portions as part of a balanced meal plan.

1. Green leafy vegetable

Green leafy vegetables are packed full of essential vitamins, minerals, and nutrients. They also have minimal impact on blood sugar levels. They are also low in digestible carbs, or carbs absorbed by the body, so they will not significantly affect blood sugar levels.

Leafy greens, including spinach and kale, are a key plant-based source of potassium, vitamin A, and calcium. They also provide protein and fiber.

Some researchers say that eating green leafy vegetables is helpful for people with diabetes due to their high antioxidant content and starch-digesting enzymes.

2. Whole Grains


Whole grains contain high levels of fiber and more nutrients than refined white grains. Eating a diet high in fiber is important for people with diabetes because fiber slows down the digestion process. Slower absorption of nutrients helps keep blood sugar levels stable.

Whole wheat and whole grains are lower on the glycemic index (GI) scale than white bread and rice. This means that they have less of an impact on blood sugar.

Good examples of whole grains to include in the diet are:

  • brown rice
  • whole-grain bread
  • whole-grain pasta
  • buckwheat
  • quinoa

People can swap white bread or white pasta for whole-grain options.

According to a recent study, it is shown that consuming 4 servings of whole grains per day can reduce the risk of developing pre-diabetes by up to 30%. Meanwhile, other research shows that if people consume whole grains daily, they also experience less inflammation, in return lowering the odds of developing insulin resistance, high blood pressure, and heart disease.

3. Fatty Fish


Some people consider fatty fish to be one of the healthiest foods on the planet.

Salmon, sardines, herring, anchovies, and mackerel are great sources of the omega-3 fatty acids DHA and EPA, which have major benefits for heart health.

Getting enough of these fats on a regular basis is especially important for people with diabetes, who have an increased risk for heart disease and stroke.

DHA and EPA protect the cells that line your blood vessels, reduce markers of inflammation, and may help improve the way your arteries function

Research indicates that people who eat fatty fish regularly have a lower risk for acute coronary syndromes, like heart attacks, and are less likely to die from heart disease

Studies show that eating fatty fish may also help regulate your blood sugar.

A study in 68 adults with overweight and obesity found that participants who consumed fatty fish had significant improvements in post-meal blood sugar levels, compared with participants who consumed lean fish.

Fish is also a great source of high-quality protein, which helps you feel full and helps stabilize blood sugar levels. For the vegetarian option, people can eat seaweed, such as kelp and spirulina, as plant-based alternative sources of these fatty acids.

4. Beans

Beans are cheap, nutritious, and super healthy.

Beans are a type of legume-rich in B vitamins, beneficial minerals (calcium, potassium, and magnesium), and fiber.

They also have a low glycemic index, which is important for managing diabetes.

Also, beans may help people manage their blood sugar levels. They are a complex carbohydrate, so the body digests them slower than it does other carbohydrates.

Eating beans can also help with weight loss and could help regulate a person’s blood pressure and cholesterol.

In a study involving more than 3,000 participants at high risk for cardiovascular disease, those who had a higher consumption of legumes had a 35 percent reduced chance of developing type 2 diabetes.

5. Nuts


Nuts are another excellent addition to the diet. Like fish, nuts contain healthy fatty acids that help keep the heart-healthy.

Walnuts are especially high in omega-3 fatty acids called alpha-lipoic acid (ALA). Like other omega-3s, ALA is important for good heart health.

Walnuts also provide key nutrients, such as protein, vitamin B-6, magnesium, and iron.

People with diabetes may have a higher risk of heart disease or stroke, so it is important to get these fatty acids through the diet.

A 2019 study involving over 16,000 participants with type 2 diabetes found that eating tree nuts — such as walnuts, almonds, hazelnuts, and pistachios — lowered their risk of heart disease and death.

Research also indicates that nuts can improve blood glucose levels.

A study in subjects with type 2 diabetes found that consumption of walnut oil daily improved blood glucose levels.

This finding is important because people with type 2 diabetes often have elevated levels of insulin, which are linked to obesity.

6. Probiotics

                                                                            
                                      Probiotics are the helpful bacteria that live in the human gut and improve digestion and overall health.

Some research from 2011 suggested that eating probiotic yogurt could improve cholesterol levels in people with type 2 diabetes. This could help lower the risk of heart disease.

One review study suggested that consuming probiotic foods may reduce inflammation and oxidative stress, as well as increase insulin sensitivity.

People can choose a natural yogurt, such as Greek yogurt, with no added sugar. A probiotic yogurt will contain live and active cultures called Lactobacillus or Bifidobacterium.

A long-term study involving health data from over 100,000 participants found that a daily serving of yogurt was linked to an 18 percent lower risk of developing type 2 diabetes.

It may also help you lose weight if that is a personal goal.

Studies show yogurt and other dairy foods may lead to weight loss and improved body composition in people with type 2 diabetes.

The high levels of calcium, protein, and a special type of fat called conjugated linolic acid (CLA) found in yogurt may help reduce your appetite, making it easier to resist unhealthy foods.

What is more, Greek yogurt contains only 6–8 grams of carbs per serving, which is lower than conventional yogurt.

It is also higher in protein, which may promote weight loss by reducing appetite and decreasing calorie intake.

The Bottom Line

People with diabetes can work with their healthcare professionals to devise a personal nutrition plan.

Eating a healthful, balanced diet including the foods listed above can help people with diabetes manage their condition and prevent complications by:

  • controlling their blood sugar levels
  • lowering inflammation
  • lowering the risk of heart disease
  • increasing antioxidant activity
  • reducing the risk of kidney disease

When diabetes is not managed, it increases your risk for several serious diseases.

Just remember, although these foods may help manage blood sugar, the most important factor in healthy blood sugar management is following an overall nutritious, balanced diet.

Hemorrhoids

What is hemorrhoids?

Hemorrhoids also knows as piles that occur inside and around the anal passage. They are quite common to be happened.
Hemorrhoids can either be internal or external. Internal hemorrhoids develop within the anus or rectum. External hemorrhoids develop outside of the anus. 
External hemorrhoids are the most common and most troublesome. Hemorrhoids cause pain, itching, bleeding and difficulty sitting. Fortunately, they are treatable.

Signs and Symptoms

Signs and symptoms of hemorrhoids usually depend on the types of hemorrhoids.

External hemorrhoids

These are under the skin around your anus. Signs and symptoms are:
– Itching and irritation in your anal region
– Pain or discomfort
– Swelling around your anus
– Bleeding

Internal hemorrhoids

Internal hemorrhoids lie inside the rectum, which usually you can’t see or feel it. But straining or irritation when passing stool can cause:
– Painless bleeding, you might notice small amount of bright red blood on toilet tissue or in the toilet.
– A hemorrhoid to push through the anal opening ( prolapsed or protruding hemorrhoid), resulting in pain or irritation.

Causes

Hemorrhoids are usually caused by constipation. Constipation can make you to strain when you go to toilet so it puts pressure on the blood vessel in the anus which ca make them become swelling.

Other things can increase the risk of getting hemorrhoids are:
– Ageing
– Being obese
– Sitting for long periods of time on the toilet
– Regularly lifting heavy things
– Straining during bowel movement
– Having diarrhea or constipation
– Pregnancy

Complications

Anemia

It is rarely happen, but chronic blood loss from hemorrhoids may cause anemia.

Strangulated Hemorrhoid

If the blood supply to an internal hemorrhoid is cut off, then the hemorrhoid may be “strangulated,” which can cause extreme pain.

Blood Clot

Occasionally, a clot can form in a hemorrhoid which know as thrombosed hemorrhoid. Although it is not dangerous, but it can cause extremely painful.

Preventions

Eat high fiber foods

Eat more fruits, vegetables and whole grains. It can help in soften the stool that will help you avoid the straining which can cause hemorrhoids and pass the stool more easily.

Drink plenty of fluids

Drink six to eight glasses of water which can help you avoid constipation.

Don’t strain

Straining when you are trying to pass a stool creates greater pressure in the veins in the lower rectum which will cause hemorrhoids.

Obesity

Obesity is another factor of hemorrhoids, and you can lose your weight by exercising regularly, consuming low fat diet and reducing consumption alcohol intake.

Good Hygiene

Practice good hygiene by cleaning your anus with warm water during a shower or bath every day and keep your bottom clean and dry. But don’t use soap, as soap can aggravate hemorrhoids. Also avoid using dry or rough toilet paper when you wipe after a bowel movement.

Treatments

Fiber supplements

Most of people don’t get the enough fiber intake daily. And studies shown that over the counter fiber supplements such as psyllium or methylcellulose improved overall symptoms and bleeding from hemorrhoids. 
But when you eat fiber supplement must be make drink enough of water daily. It can cause constipation if it does not.

Sitz bath

A sitz bath is referred to sitting a few inches of warm water 3 times a day for 15 to 20 minutes. A sitz bath may help in decrease the inflammation of hemorrhoids. Drying off the anal area completely after sitz bath which can minimize the moisture that can irritate the skin around your rectal area. 

Medical procedures

If home treatments aren’t helping with your hemorrhoids, your doctor might recommend getting a rubber band ligation. This procedure involves the doctor cutting off circulation to the hemorrhoid by placing a rubber band around it.
This causes loss of circulation to the hemorrhoid, forcing it to shrink. This procedure should only be performed by a medical professional.

Sun Protection 101: Protect Your Skin from the Sun

Ever wonder how strong the sunlight in Malaysia is?

Putting aside the scorching temperature and blinding brightness, there’s something within Malaysia’s sunlight that is more worrying – Ultraviolet radiation (UV).  According to the Who Health Organisation (WHO) INTERSUN program, the level of UV radiation can be measured using UV Index such as below:


And unsurprisingly, Malaysia in general is usually exposed under UV index 9 to 11+ most of the time all year round.

You may wonder what’s the big deal about UV radiation.

To understand that we’ll need to look into the types of UV radiation that we are commonly exposed to in the atmosphere – UVA and UVB.


Up to 95% of the UV radiation that reaches Earth’s surface is UVA. UVA rays are much more prevalent on Earth and are always present regardless of season or time of day due to its longer wavelength giving it the ability to penetrate through clouds and glass. Although they are less intense than UVB, UVA can penetrate the skin more deeply and cause skin aging and wrinkling. Exposing to UVA also leads to injury in the DNA of the skin. In order to prevent further DNA damage, the skin darkens, causing skin tanning. Even though UVA does not cause significant damage to the epidermis, the outermost layer of skin where most skin cancers occur, they do still bring damage to a deeper layer of the epidermis and thus still contribute to and may initiate skin cancer to develop.

UVB on the other hand is known to be the main reason our skin reddens and gets sunburn when exposed to sunlight for too long. Because of their shorter wavelength, they can only reach and damage the more superficial layer of the epidermis, but they play a big role in the development of skin cancer. UVB intensity varies throughout the day and usually is most intense between 11.00 am to 3.00 pm in Malaysia. UVB does not pass through glass significantly, but it can be reflected and bounce back on a reflective surface, hitting your skin twice.

So to summarise:

UVAUVB
Cause skin aging, wrinkling and darkeningCause skin redness and sunburn
Present all daylight with equal intensityStrength varies on time of day
Can penetrate glass and cloudCannot penetrate glass
Contribute to skin cancer of deeper layerContribute to skin cancer of superficial layer
Shield by PA+Shield by SPF


So how do we protect ourselves from the harm of UV rays?

One way is to apply sunscreen or sunblock. To evaluate how effective the sunscreen is, you can look at its Sun Protection Factor (SPF). The SPF value of a sunscreen indicates how much longer it will take for your skin to redden and get sunburnt by UVB rays when the sunscreen is applied, compared to when you do not apply any sunscreen. If you usually get sunburnt within 10 minutes under the sun when not applying sunscreen, applying a sunscreen with SP15 will delay the time till sunburnt to 15 times longer. So now your skin takes 150 minutes to get sunburnt.

Some of you may think: What if I want to prevent my skin from darkening because of sunlight exposure?  Then you should be checking out the PA value of the sunscreen. Basically, the more + is added to the back of PA, the better the protection against UVA.

•             PA+ = Some UVA protection.

•             PA++ = Moderate UVA protection.

•             PA+++ = High UVA protection.

•             PA++++ = Extremely High UVA protection.

Since we want to reduce the damage of both UVA and UVB, it is always better to look for broad-spectrum sunscreen and provides protection towards both types of UV rays.

Here we recommend you always use a broad-spectrum sunscreen with at least SPF 15 for daily activity. However, for extended outdoor activities, at least SPF 30 sunscreen should be applied. Keep in mind that sunscreens will start to lose effectiveness over time regardless of its SPF value, so it is important to reapply them every 2 hours. If you are going for a swim or activities that will cause heavy sweating, choose a sunscreen that indicates water-resistant or sweat resistant. Water-resistant sunscreen will remain effective for 40 minutes when swimming while sweat-resistant sunscreen will last 80 minutes when sweating. There is no “waterproof” or “sweatproof” sunscreen so you will still need to reapply the sunscreen frequently.  In order to let sunscreen function properly, always apply it 30 minutes before going out.

UPF RatingProtection CategoryEffective UV Transmission (%)
15, 20Good6.7-4.2
25, 30, 35Very Good4.1-2.6
40, 45, 50, 50+ExcellentLess than 2.5

Apart from using sunscreen, you can protect yourself from UV rays by wearing clothing with UV cutting properties. Look for clothes with higher UPF (Ultraviolet Protection Factor). The higher the UPF, the less UV can penetrate through the clothing. Clothing with a UPF rating of 30 will allow only 1/30th (about 3 percent) of UV to pass through it and the UPF rating of 50 will only let 2 percent of UV to penetrate.

Even if you are unable to find clothes that claim to have UPF, you can choose to wear more tightly-woven but loose-fitting clothing as they provide more barrier between your skin and the sun. Clothes made from mixture or fully heavyweight natural fabrics like cotton, linen and light synthetic fabrics like polyester, nylon and spandex are some of the good choices. Wearing darker and more vibrant colour clothing will also absorb more UV and prevent them from reflecting other parts of your body when compared to clothing with pale colours. Remember clothes will also start to stretch and lose their colour after being worn and washed for some time, and therefore loses some of its sun-protective effects. So I guess that gives us more reason to buy new clothes once in a while.

Even with the above precautions taken, it is still best to stay in the shade as much as possible when going out. Wearing UV-blocking sunglasses and wide-brimmed hats helps too.

Hopefully, with this, you will be able to protect yourself from the damage of UV better in the future. Stay healthy, stay safe!



Nutrition and Chronic Kidney Disease (CKD)

Chronic kidney disease (CKD) is marked by long term, irreversible loss of function. Since it is irreversible, what we can do is only slow down its progress to end-stage renal disease (ESRD) which requires dialysis. Diabetes and high blood pressure are the most common causes of CKD. For the person having diabetes or high blood pressure, working with doctor to keep blood sugar and blood pressure under control is the best way to prevent kidney disease.

Why is good nutrition important for people with CKD?

Making healthy food choices is important to us all, but it is even more important if you have chronic kidney disease. Good nutrition gives you energy to:
– Do your daily tasks
– Prevent infection
– Build muscle
– Help maintain a healthy weight
– May keep your kidney disease from getting worsen

Will I need to control any other nutrients?

When your kidneys are not working as well as they should, waste and fluid build up in your body. Over time, the waste and extra fluid can cause heart, bone and other health problems.
You may need to balance fluids and other nutrients. There are:
– Sodium
-Phosphorus
-Potassium

SODIUM

Sodium is a mineral found in most foods. It is also found in table salt. Sodium affects blood pressure and water balance in body. If your kidneys do not work well, sodium and fluid build up in your body. This can cause high blood pressure and other problems, like swelling of ankles.

You can limit sodium by avoiding table salt and foods such as:
– Seasonings like soy sauce, sea salt, teriyaki sauce
– Most canned foods and frozen foods
– Processed meats like ham, bacon, hot dog, sausage
– Salted snack foods like chips and crackers


POTASSIUM

Potassium is a mineral found in almost all foods. Your body need some potassium to make your muscles work, but too much potassium can be dangerous. When your kidneys are not working well, your potassium level may be too high or too low.
Having too high or too low of potassium can cause muscle cramps, problems with heart beats and muscles weakness.

Use the list below to get some ideas about how to make healthy choices if you need limit potassium.

Eat this.. (Lower potassium foods)
Avoid this.. (High potassium foods)
Apples, cranberries
Oranges, Banana, Avocado, Prunes
Carrots, Onions
Potatoes, Tomatoes
White rice
Brown rice
Cauliflower, lettuce
Dairy foods (milk, yogurt)
Beef and chicken
Whole-wheat bread and pasta

Beans and nuts



PHOSPHORUS

Phosphorus is a mineral found in almost all foods. It works with calcium and vitamin D to keep your bones healthy. Healthy kidneys keep the right amount of phosphorus in your body. When your kidneys are not working well, phosphorus can build up in your blood. Too much phosphorus in your blood can lead to weak bones that break easily.

Use the list below to get some ideas about how to make healthy choices if you need limit potassium.


Eat this.. (Lower phosphorus foods)
Avoid this.. (High phosphorus foods)
Italian, French bread
Bran cereals and oatmeal
Fresh fruits and vegetables
Dairy foods
Corn or rice cereals
Beans and nuts
Some light-colored sodas (homemade iced tea or lemonade)
Dark-colored colas


FLUIDS

You need water to live, but when you have kidney disease, you may not need much water. This is because damaged kidneys do not get rid of extra fluids as well as they should. Too much fluids in your body can be dangerous. It can cause high blood pressure, swelling and heart failure. Extra fluid can also build up around your lungs and make it hard to breathe.

Depending on your stage of kidney disease, your doctor may tell you to limit fluid. To avoid dehydration, let your doctor help plan your fluids intake.


Breastfeeding


1. DATA & STATISTIC OF BREASTFEEDING

Breastfeeding provides numerous benefits for mothers and their children. However, currently, only 40% of the global average rate of infants below six months of age was exclusively breastfed, with only 23 countries managed to achieve rates of 60% or higher. World Health Organization (WHO) Global Nutrition Targets 2025 has set targets to achieve at least 50% rate of exclusive breastfeeding among members’ countries. The National Plan of Action for Nutrition of Malaysia III (NPANM III), 2016-2025 has set another indicator to achieve at least 70% of infants below 6 months of age to be exclusively breastfed by 2025.

In Malaysia, the prevalence of exclusive breastfeeding was 19.3% in 2006 and has increased to 47.1% in 2016. Even though there was an increment, this was still less than the targeted prevalence set by WHO and NPANM III.

2. BENEFITS OF BREASTFEEDING

Benefits of Breastfeeding 


Children who are breastfed experience improved dental health and neuro developmental outcomes. They have decreased risk of:

  • Otitis media
  • Diarrhoea
  • Respiratory tract infection
  • Necrotizing enterocolitis
  • SIDS
  • Atopic dermatitis
  • Asthma
  • Celiac Disease
  • Crohn’s Disease and ulcerative colitis
  • Late-onset sepsis in preterm infants
  • Type 1 and type 2 diabetes
  • Leukaemia
  • Childhood overweight and obesity

Maternal Benefits

There are also maternal health benefits to breastfeeding such as decreased risk of the following:

  • Decreased excessive menstrual blood loss
  • Breast, ovarian, endometrial and thyroid cancers
  • Hypertension
  • Type 2 diabetes
  • Rheumatoid Arthritis

Breastfeeding is also a great benefit to the environment and society. It was shown that breastfeeding families become sick less often and the parents miss work less. Breast milk will be always available, at the right temperature and ready to be fed,there is no risk of contamination, even in the case of emergency situations, such as natural disasters.

3. HOW MUCH & HOW OFTEN TO BREASTFEED

One of the most common questions new parents have is how often their baby should be fed. The best answer is surprisingly simple: in general, babies should be fed whenever they seem hungry.

Every baby is different. How much and how often your baby feeds will depend on your baby’s needs. Here are a few things to know about how much and how often babies breastfeed during the first days, weeks, and months of life.

First Days

  • Your newborn baby’s belly is tiny. He or she does not need a lot of milk with each feeding to be full.
  • Your baby may want to eat as often as every 1 to 3 hours. Frequent feeding helps increase your milk supply and gives your baby practice at sucking and swallowing.
  • You may be able to hear your baby sucking and swallowing the breast milk.
  • Most babies who are getting breast milk should not be fed infant formula in the first few days. If you are concerned about meeting your baby’s needs, talk to a lactation consultant, or your baby’s nurse or doctor, right away to find out how to address any breastfeeding problems and determine the best way to meet your baby’s needs.

First Weeks and Months

  • Over the first few weeks and months, the time between feedings will start to get longer— on average about every 2 to 4 hours for most exclusively breastfed babies. Some babies may feed as often as every hour at times, often called cluster feeding, or may have a longer sleep interval of 4 to 5 hours.
  • How often your baby feeds might change depending on the time of day. Some feeding sessions may be long, and others short. That is okay. Babies will generally take what they need at each feeding and stop eating when they are full. They should seem content and drowsy after feeding when they have had enough milk.
  • Your baby will breastfeed about 8 to 12 times in 24 hours.

6 to 12 Months

  • Breastfed babies’ feeding patterns (how often and how long they feed) vary and will likely change as they grow and start eating more solid foods.
  • If your baby seems to be less interested in breastfeeding after you introduce solids, try breastfeeding first before you offer solids.
  • Your breast milk is the most important source of nutrition, even after you start feeding your baby solids.

12 to 24 Months

  • The number of times a day a toddler breastfeeds varies. Some want to breastfeed only before bed or in the morning, while others continue to drink breast milk as a bigger portion of their daily diet. Continue to follow your child’s cues to decide when he or she is hungry and wants to breastfeed.

4. PROPER STORAGE & PREPARATION

  • Wash your hands well with soap and water. If soap and water are not available, use an alcohol-based hand sanitizer that contains at least 60% alcohol.
  • Mothers can express breast milk by hand or with a manual or electric pump.
  • If using a pump, inspect the pump kit and tubing to make sure it is clean. Discard and replace mouldy tubing immediately.
  • If using a shared pump, clean pump dials, power switch, and countertop with a disinfectant wipe.

Storing breast milk after expressing:

  • Use breast milk storage bags or clean, food-grade containers to store expressed breast milk. Make sure the containers are made of glass or plastic and have tight fitting lids.
    • Avoid bottles with the recycle symbol number 7, which indicates that the container may be made of a BPA-containing plastic.
  • Never store breast milk in disposable bottle liners or plastic bags that are not intended for storing breast milk.
  • Freshly expressed or pumped milk can be stored:
    • At room temperature (77°F or colder) for up to 4 hours.
    • In the refrigerator for up to 4 days.
    • In the freezer for about 6 months is best; up to 12 months is acceptable. Although freezing keeps food safe almost indefinitely, recommended storage times are important to follow for best quality.

Storage tips:

  • Clearly label the breast milk with the date it was expressed.
  • Do not store breast milk in the door of the refrigerator or freezer. This will help protect the breast milk from temperature changes from the door opening and closing.
  • If you don’t think you will use freshly expressed breast milk within 4 days, freeze it right away. This will help to protect the quality of the breast milk.
  • Breast milk can be stored in an insulated cooler with frozen ice packs for up to 24 hours when you are traveling. At your destination, use the milk right away, store it in the refrigerator, or freeze it.

Safe Thawing of Breast Milk

  • Always thaw the oldest breast milk first. Remember first in, first out. Over time, the quality of breast milk can decrease.
  • There are several ways to thaw your breast milk:
    • In the refrigerator overnight.
    • Set in a container of warm or lukewarm water.
    • Under lukewarm running water.
  • Never thaw or heat breast milk in a microwave. Microwaving can destroy nutrients in breast milk and create hot spots, which can burn a baby’s mouth.
  • If you thaw breast milk in the refrigerator, use it within 24 hours. Start counting the 24 hours when the breast milk is completely thawed, not from the time when you took it out of the freezer.
  • Once breast milk is brought to room temperature or warmed, use it within 2 hours.
  • Never refreeze breast milk after it has thawed.

Feeding Expressed Breast Milk

  • Breast milk does not need to be warmed. It can be served room temperature or cold.
  • If you decide to warm the breast milk, here are some tips:
    • Keep the container sealed.
    • Place the sealed container into a bowl of warm water or hold it under warm, but not hot, running water for a few minutes.
    • Test the milk’s temperature before feeding it to your baby by putting a few drops on your wrist.
    • Do not heat breast milk directly on the stove or in the microwave.
  • Swirl the breast milk to mix the fat, which may have separated.
  • If your baby did not finish the bottle, use the leftover milk within 2 hours after the baby is finished feeding. After 2 hours, leftover breast milk should be discarded.

5. CONTRAINDICATION

  • Mothers should NOT breastfeed or feed expressed breast milk to their infants if

    • Infant is diagnosed with classic galactosemia, a rare genetic metabolic disorder
    • Mother is infected with the human immunodeficiency virus (HIV) (Note: recommendations about breastfeeding and HIV may be different in other countries)
    • Mother is infected with human T-cell lymphotropic virus type I or type II (HTLV – 1/2)
    • Mother is using an illicit street drug, such as PCP (phencyclidine) or cocaine (Exception: Narcotic-dependent mothers who are enrolled in a supervised methadone program and have a negative screening for HIV infection and other illicit drugs can breastfeed)
    • Mother has suspected or confirmed Ebola virus disease

    Mothers should temporarily NOT breastfeed and should NOT feed expressed breast milk to their infants if

    • Mother is infected with untreated brucellosis
    • Mother is taking certain medications
    • The mother is undergoing diagnostic imaging with radiopharmaceuticals
    • Mother has an active herpes simplex virus (HSV) infection with lesions present on the breast  (Note: Mothers can breastfeed directly from the unaffected breast if lesions on the affected breast are covered completely to avoid transmission)

    In conclusion, mothers may resume to breastfeeding after consulting with a physician to determine when their breast milk is safe for their infant.

    Mothers should temporarily NOT breastfeed, but CAN feed expressed breast milk if

    • Mother has untreated, active tuberculosis

    (Note: The mother may resume breastfeeding once she has been treated appropriately for 2 weeks and is documented to be no longer contagious)

    • Mother has active varicella (chicken pox) infection that developed within the 5 days prior to delivery to the 2 days following delivery

    In conclusion, airborne and contact precautions may require temporary separation of the mother and infant, during which time expressed breast milk should be given to the infant by another care provider. Mothers should be able to resume breastfeeding after consulting with a physician to determine when there is no longer a risk of spreading infection.

    Are medications safe to take while breastfeeding?

    Few medications are contraindicated while breastfeeding. Although many medications do pass into breast milk, most have no known adverse effect on milk supply or on infant well-being. So, kindly consult your doctor if you have any doubts.

6. COVID-19 & BREASTFEEDING Q&A


    1. Can COVID-19 be passed through breastfeeding?

    Ans: Transmission of active COVID-19 (virus that can cause infection) through breast milk and breastfeeding has not been detected to date. There is no reason to avoid or stop breastfeeding.

    1. Should mothers breastfeed in communities where COVID-19 is prevalent?

    Ans: Yes. In all socio-economic settings, breastfeeding improves survival and provides lifelong health and development advantages to newborns and infants. Breastfeeding also improves the health of mothers.

    1. Following delivery, should a baby still be immediately placed skin-to-skin and breastfed if the mother is confirmed or suspected to have COVID-19?

    Ans: Yes. Immediate and continued skin-to-skin care, including kangaroo mother care, improves the temperature control of newborns and is associated with improved survival among newborn babies. Placing the newborn close to the mother also enables early initiation of breastfeeding which also reduces mortality.

    The numerous benefits of skin-to-skin contact and breastfeeding substantially outweigh the potential risks of transmission and illness associated with COVID-19.

    1. Can women with confirmed or suspected COVID-19 breastfed?

    Ans: Yes. Women with confirmed or suspected COVID-19 can breastfeed if they wish to do so. They should:

    • Wash hands frequently with soap and water or use alcohol-based hand rub and especially before touching the baby
    • Wear a medical mask during any contact with the baby, including while feeding
    • Sneeze or cough into a tissue. Then dispose of it immediately and wash hands again
    • Routinely clean and disinfect surfaces that mothers have touched.

    It is important to replace medical masks as soon as they become damp and dispose of them immediately. Masks should not be reused or touched in the front.

    1. If a mother confirmed or suspected to have COVID-19 does not have a medical face mask should she still breastfeed?

    Ans: Yes. Breastfeeding unquestionably reduces mortality in newborns and infants and provides numerous lifelong health and brain development advantages to the child.

    Mothers with symptoms of COVID-19 are advised to wear a medical mask, but even if this is not possible, breastfeeding should be continued. Mothers should follow other infection prevention measures, such as washing hands, cleaning surfaces, sneezing or coughing into a tissue.

    1. If a mother has confirmed or suspected COVID-19 and is too unwell to breastfeed her baby directly. What can she do?

    Ans: If you are too unwell to breastfeed your baby due to COVID-19 or other complications, you should be supported to safely provide your baby with breast milk in a way possible, available, and acceptable to you. This could include:

    • Expressing milk
    • Donor human milk. 

    If expressing breast milk or donor human milk are not feasible then consider wet nursing (another woman breastfeeds the child) or infant formula milk with measures to ensure that it is feasible, correctly prepared, safe and sustainable.

    1. If a mother had confirmed or suspected COVID-19 and was unable to breastfeed, when can she start to breastfeed again?

    Ans: You can start to breastfeed when you feel well enough to do so. There is no fixed time interval to wait after confirmed or suspected COVID-19. There is no evidence that breastfeeding changes the clinical course of COVID-19 in a mother. Health workers or breastfeeding counsellors should support you to relactate.

    1. If a mother has confirmed or suspected COVID-19, is it safer to give her baby infant formula milk?

    Ans: No. There are always risks associated with giving infant formula milk to newborns and infants in all settings. The risks associated with giving infant formula milk are increased whenever home and community conditions are compromised, such as reduced access to health services if a baby becomes unwell, reduced access to clean water and/or access to supplies of infant formula milk are difficult or not guaranteed, affordable and sustainable.

    The numerous benefits of breastfeeding substantially outweigh the potential risks of transmission and illness associated with the COVID-19 virus.

    1. Can a breastfeeding woman get vaccinated against COVID-19?

    Ans: Yes, women who are breastfeeding can take the vaccine when it becomes available to them.   

    None of the currently approved vaccines use the live virus, so there is no risk of passing the virus to the baby through breastmilk.  

    There is also some evidence that, after vaccination, antibodies are found in breastmilk, which may help protect the baby against COVID-19.

7. SUPPLEMENTS FOR BREASTFEEDING MOTHER

  • Supplements for breastfeeding mothers:

    1. Omega-3 fatty acids 

    Omega-3 fatty acids are essential to support baby’s brain, eye, immune system and nervous system development. Studies also show that maternal supplementation of omega-3 fatty acids during breastfeeding can reduce food allergies and eczema in baby.

    2. Calcium and vitamin D

    The recommended daily intake of calcium for breastfeeding women is 1200mg/day while an estimated of 600IU (15mcg) of vitamin D is required. Calcium is vital for the bone and teeth formation of baby while vitamin D is needed for calcium absorption.

    3. Iodine

    Babies require iodine for proper growth, development of brain, visual motor skills and hearing. Since breastfed babies depend on breast milk alone as their source of iodine, breastfeeding mothers need to get enough iodine for the baby and themselves. It is recommended that breastfeeding mothers take an iodine supplement of 150mcg per day.

    4. Vitamins B Complex (Vitamin B1, B2, B3, B5, B6, B7, B9, B12)

    Vitamins B group is important for the nervous system development and production of red blood cells. Since they are water-soluble and our bodies do not store them, daily supplementation is needed. These vitamins are mostly obtained from animal food sources and not found in plant-based food. Therefore, it is also crucial for breastfeeding mothers who are vegetarian to take supplements containing vitamin B group.

    5. Fenugreek

    Fenugreek is a herb that is commonly used as a galactagogue to increase breast milk production. Studies indicate that fenugreek may have mild galactagogue effect. Fenugreek can be taken in the form of capsules, powder mixed with drinks or tea, typically in doses of 1-6g daily. It is considered safe in nursing mothers but should be used with caution in people with diabetes as it can lower blood sugar if taken at higher doses.

    Although not considered harmful when used in moderation, fenugreek can cause your breastmilk, sweat, and urine to smell like maple syrup. Your baby’s urine and sweat may start to smell like maple syrup, too. Note that the latter should not be confused with maple syrup urine disease.

    6. Lecithin

    Lecithin is a phospholipid elements. It’s thought to help prevent the breast ducts from getting plugged by increasing the polyunsaturated fatty acids in the milk and decreasing its stickiness. A plugged duct occurs when the milk passageways in the breast become blocked.Reference:

    1. Farahana Mohamad Pilus, Norliza Ahmad, Nor Afiah Mohd Zulkefli. 2019. Predictors of Exclusive Breastfeeding Among Mothers Attending Rural Health Clinics in Hulu Langat District. Malaysian Journal of Medicine and Health Sciences (eISSN 2636-9346). Mal J Med Health Sci 15(SP3): 15-21.American Academy of Pediatrics. 2021. Breastfeeding Overview.
    2. Sanjeev Jain, MD, FAAP. 2020. How Often and How Much Should Your Baby Eat? American Academy of Pediatrics.
    3. Centre of Disease Control and Prevention. 2020. Nutrition: How Much and How Often to Breastfeed.
    4. Centers of Disease Control and Prevention. 2021. Breastfeeding: Proper Storage and Preparation of Breast Milk.
    5. American Academy of Pediatrics. 2021. Breastfeeding Overview.
    6. Centres of Disease Control and Prevention. 2019. Breastfeeding: Contraindication.
    7. World Health Organization. 2020. Coronavirus disease (COVID-19): Breastfeeding Q&A.
    8. 1.Cacho N, Lawrence R. Innate Immunity and Breast Milk. Frontiers in Immunology. 2017;8(584).
    9. 2.World Health Organization. Global Strategy for Infant and Young Child Feeding: The Optimal Duration of Exclusive Breast Feeding. 54th World Health Assembly. Document A54/INF.DOC./4. World Health Organization; Geneva: 2001.
    10. 3.Australian National Health and Medical Research Council (NHMRC). 2013 Australian Dietary Guidelines. National Health and Medical Research Council. Canberra: 2013.
    11. 5.Gunaratne A, Makrides M, Collins C. Maternal prenatal and/or postnatal n-3 long chain polyunsaturated fatty acids (LCPUFA) supplementation for preventing allergies in early childhood. Cochrane Database of Systematic Reviews. 2015;(7).
    12. 6.Kominiarek M, Rajan P. Nutrition Recommendations in Pregnancy and Lactation. Medical Clinics of North America. 2016;100(6):1199-1215.
    13. 7.Leung A, Pearce E, Braverman L, Stagnaro-Green A. AAP Recommendations on Iodine Nutrition During Pregnancy and Lactation. Pediatrics. 2014;134(4):e1282-e1282.
    14. 8.Allen L. B Vitamins in Breast Milk: Relative Importance of Maternal Status and Intake, and Effects on Infant Status and function. Advances in Nutrition. 2012;3(3):362-369.
    15. 9.Fenugreek. Bethesda: U.S. Dept. of Health and Human Services, National Institutes of Health, National Center for Complementary and Alternative Medicine; 2012.
    16. 10.Sim T, Hattingh H, Sherriff J, Tee L. The Use, Perceived Effectiveness and Safety of Herbal Galactagogues During Breastfeeding: A Qualitative Study. International Journal of Environmental Research and Public Health. 2015;12(9):11050-11071.
    17. Donna Murray. 2021. 10 Herbs to Increase Breast Milk Supply.
    18. Jacquelyn Cafasso. 2016. Using Lecithin While Breast-Feeding for Plugged Ducts.

Myths and Facts of Covid-19

On 31 December 2019, there was an unknown cause that gave rise to pneumonia cases in Wuhan City, China. It was not long until the World Health Organization (WHO) was informed of a new Coronavirus Disease, which is known as COVID-19, until present 2021.

This infectious disease infects human beings, leading to them experiencing mild to moderate respiratory illness and recovering without requiring special treatment. 

However, there are cases where elderly and population with underlying medical conditions such as cardiovascular disease, diabetes mellitus, respiratory disease, and cancer are more prone to develop serious symptoms.

Covid-19 has been existing from 2019 until the present day, there have been plenty of questions and doubts regarding this disease. Here are 8 myths and facts about this highly infectious disease that were found to be closely related to our daily life.

1. Can Covid-19 virus be transmitted through goods, cash and groceries?

  • Yes. Covid viruses can stay on the surface for many hours and up to days. Examples such as metal products can have the virus survive up to 9 days, woods up to 4 days, plastic surface up to 3 days and etc.
  • Thus, it is better to be safe than sorry. It is strongly suggested to disinfect items’ surfaces and frequently-touched objects using a disinfecting spray or wipe.
  • As for groceries such as fruits and vegetables, rinsing them in cold water or cleaning with vegetable brushes are adequate. Using disinfecting spray, wipe or soap can lead to possible food poisoning.

2. Are insects such as mosquitoes and houseflies, possibly carriers that spread Covid-19?

  • Currently there is no evidence that covid viruses can be transmitted through insects. However, proper protection against mosquitoes are still required to protect against disease such as dengue fever, malaria, etc.


3. Is the virus able to stick to our clothes and shoes?

  • There’s not much research about how long the virus lives on fabric.
  • The possibility of COVID-19 being spread on shoes and infecting individuals is very low as well. As a safeguard, especially when there are infants and small children crawling or playing on floors, do remove the shoes before entering home.
  • It is also recommended that proper hygiene needs to be practised, besides from showering every day, clothes should be washed with detergent or soap in 60-90 ⁰C water, drying clothes under a hot sun or in a high temperature dryer can help to kill the virus as well.


4. Can Covid-19 be prevented by rinsing the nasal cavity with saline solution? Besides, is gargling with mouthwash, warm water with salt or vinegar solution proven to prevent viruses and other things to travel into the throat and lung?

  • Evidence has shown that rinsing the nose with saline solution can help the patient to recover faster from the common cold symptoms, but unable to prevent Covid-19 and other infectious respiratory diseases such as pneumonia.
  • Moreover, the Centers for Disease Control and Prevention (CDC) suggested that gargling with warm salty water can help with soothing a sore throat, but not effective in stopping infection with Covid-19.

5. Are there any medications that can prevent and cure Covid-19? 

  • There has been news where medications such as oral steroids, hydroxychloroquine, azithromycin and Ivermectin are claimed to be able to treat or prevent Covid-19.
  • Oral steroids such as Dexamethasone have anti-inflammatory and immunosuppressive effects, which only should be used for Covid-19 patients with severe and critically ill conditions. For some Covid-19 patients on ventilators, a daily 6 mg dose of dexamethasone for 10 days may improve their health.
  • Dexamethasone provides no improvement for patients with mild symptoms.
  • As for hydroxychloroquine and azithromycin, randomized clinical trials and studies have been conducted to evaluate the safety and efficacy of these medications.
  • In conclusion, The COVID-19 Treatment Guidelines Panel does not recommend the use of azithromycin, chloroquine, or hydroxychloroquine for the treatment of COVID-19 in both hospitalised and non-hospitalised patients.
  • On the other hand, while initial research is still ongoing, FDA has neither approved nor supported the use of ivermectin to treat or to prevent COVID-19.
  • All in all, currently there is no drug approved that is able to prevent and treat Covid-19 disease and taking a drug for an unapproved use can be very dangerous. Misinformation and misuse of medications can lead to overdose, side effects and contraindications that can be fatal. Patients with covid symptoms should receive proper and supportive care to alleviate the symptoms.


6. Can drinking alcohol or eating garlic help to prevent Covid-19?

  • Drinking alcoholic beverages, such as wine, beer or liquor doesn’t help to prevent Covid-19. Besides, alcohol is known to harm human health and is associated with a range of diseases. Alcohol can also compromise one’s immune system; increase the risk of adverse health outcomes, leading to the person more vulnerable to Covid virus. 
  • Garlic, though is known to have antimicrobial properties and used in public to prevent disease such as cold, there has been no evidence that it can help to prevent or cure Covid-19.


7. Do UV bulbs, disinfectants such as bleach or chlorine help to kill Covid-19 viruses on our body?

  • First of all, it does not help with killing the virus inside the body. Besides, do not use UV bulbs, high concentration alcohol or chlorine on your hands or any part of the body because it can irritate your skin, damage body tissues such as eyes and lips.
  • As advised by the Centers for Disease Control and Prevention (CDC), the best way to prevent the spread of coronavirus and reduce the likelihood of getting infected is by washing our hands with soap and water for at least 20 seconds, especially after going to the bathroom; before and after meals; and after coughing, sneezing, or blowing one’s nose.
  • If soap and water are not available, alcohol-based hand sanitizer that contains at least 60% alcohol should be used.


8. Do vitamin and mineral supplements contribute to preventing and healing patients from Covid-19?

  • Micronutrients, such as vitamin B, C, D, E, zinc and magnesium, are important to maintain a well-functioning immune system and play a vital role in promoting health and nutritional well-being. 
  • However, there is currently no guidance on the use of micronutrient supplements as a treatment of COVID-19.


In summary, prevention is better than cure. Always protect yourself by following the standard operation procedure (SOP) such as wear mask properly, stay at least 1m from others, get vaccinated, avoid crowds and unventilated area, practice washing and sanitizing hands often, cover coughs and sneezes with hands, clean and disinfect frequently touched area, monitor your health daily and seek for health professionals if required.


INDIGESTION

Indigestion is a condition which can be pain or discomfort in your upper abdomen (Dyspepsia) or burning pain behind the breastbone (Heartburn).

Dyspepsia and heartburn may occur together or on their own.

SYMPTOMS

– Feeling sick
– Feeling uncomfortably full or heavy
– Feeling full or bloated
– Belching or farting
– Bringing up food or bitter-tasting fluids or food into your mouth
– Heartburn, a painful burning feeling in the chest, often after eating

CAUSES

1) Medications
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, naproxen are one class of medications that can affect your digestive tract and cause indigestion.

2) Obesity
If you are very overweight, you are more likely to experience indigestion because of increased pressure inside your stomach. The increased pressure, particularly after a heavy meal, may lead to acid reflux into the oesophagus.

3) Overeating or eating too fast

4) Fatty, spicy and acidic foods

5) Smoking & drinking too much alcohol

6) Stress and anxiety

TREATMENTS

Medications

A) Antacids (Maalox plus)
Antacids are a type of medicine that can provide immediate relief for mild to moderate symptoms of indigestion. They work by neutralising the acid in your stomach (making it less acidic), so that it no longer irritates the lining of your digestive system.
B) Proton pump inhibitor (Controloc, Vencid), which can reduce stomach acid. PPIs may be recommended if you experience heartburn along with indigestion.
C) Histamine-2 Blockers (Famotidine), which can also reduce stomach acid.
D) Prokinetics (Motilium), which may be helpful if your stomach empties slowly.
E) Alginates (Gaviscon).
Some antacids contain a medicine called as alginate. This helps relieve indigestion caused by acid reflux. Alginates form a foam barrier that floats on the surface of your stomach contents, keeping stomach acid in your stomach and away from your oesophagus.

Alternative Treatments

A) Probiotics (Megalive FloraMax Plus, Megalive Flora 60 Plus, Hexbio, Bioflor), good bacteria exist in gut can limit the growth of bad bacteria and improve gut function.
B) Digestive Enzymes (Blackmores Digestive)
C) Aloe Vera Juice (Lifestream Aloe Vera Juice), reduce reflux symptoms by reducing acid production, boosting digestion and having anti-inflammatory properties.
D) Ginger helps to speed up emptying of stomach, thus helps in relieving indigestion and heartburn.

DIET



LIFESTYLE REMEDIES

– Eating smaller and more frequent meals. Chew your food slowly and completely.

– Do not chew with your mouth open, talk while chewing or eat quickly. This causes you to swallow air and can aggravate indigestion.

– Maintaining a healthy weight. Excess weight put pressure on your stomach, making it easier for stomach acid to be pushed back up into your oesophagus. This is known as acid reflux, and is one of the most common causes of indigestion.

– Avoid late night eating for three to four hours before you go to bed. Going to bed with a full stomach means there is an increased risk that acid in your stomach will be forced up into your oesophagus while you are lying down.

– Quit smoking. If you smoke, the chemicals you inhale in cigarette smoke may contribute to your indigestion.

– Drink fluids after meals, rather than during meals.

– Avoid alcoholic beverages

– Avoid drinks that contain caffeine – such as tea, coffee and cola.

– Avoid spicy and greasy foods.

– Managing stress. Practice relaxation techniques such as deep breathing, meditation or yoga.

Diabetes


What is Diabetes?

You may have heard that diabetes is a silent killer, because it takes away your life, parts by parts. The prevalence of diabetes has became worse as the year goes by as a recent survey from Health Ministry showed that nearly one in five Malaysian adults, or 18.3%, has diabetes.

Diabetes is a health disorder in when our body does not produce enough or respond normally to insulin, resulting in a buildup of extra sugar in our bloodstream.

What is Insulin?

Insulin is a type of hormone released from the pancreas that regulates the amount of glucose in the blood by helping the glucose to move from the blood into the cells.

Types of Diabetes

 Type 1 DiabetesType 2 Diabetes
What is happening?Caused by autoimmune disease when the pancreas produces too little or no insulinPancreas produces insulin, but the body doesn’t respond normally to the insulin produced.
Age of onsetChildhoodAdulthood
Risk  factorNo known cause, and there is no way to reverse or cure it. Not associated with excess body weight, some affected patients might even be underweight.Commonly associated with poor lifestyle and diet, such as excess body weight, age, physical inactivity, race and ethnicity, family history and poor control of blood lipid profile.
ManagementRequired insulin therapyCan be managed by lifestyle modification such as diet and exercise if diagnosed early. Medication can be prescribed by doctor.
Cure and preventionCannot be preventedCan be prevented by lifestyle changes

Diabetes Diagnosis

Pancreas is a gland located behind the stomach in the upper left abdomen. Pancreas will release insulin as sugar metabolism. Insulin plays an important role in keeping blood glucose level within a healthy normal range. Thus, some tests can be conducted to check whether you are diabetic. Following tests are available at pharmacy:-

  1. Glycosylated Hemoglobin (HbA1C) measures your average blood glucose level for the past 3 months. It measures how much of glucose attached to your Hb (hemoglobin) as our Hb only lives for about 3 months. This test is shown to have higher sensitivity of identifying risk of diabetes. Reduction of HbA1C significantly reduces diabetes complications. HbA1C should always be less than 6.5%.
  2. Fasting Plasma Glucose (FPG) measures blood glucose level after fasting for at least 8 hours. It is usually done in the morning without breakfast; only plain water is allowed. Fasting glucose level should be below 5.6 mmol/L.
  3. Random Plasma Glucose (RPG) measures the blood glucose level at anytime of the day. RPG should be less than 8.0 mmol/L.

Symptoms of Diabetes


Sources: Accu-chek.co.uk/sign and symptoms of diabetes

The common term to remember is The 3 P’s of Diabetes, which is

  1. Increased hunger (Polyphagia) – The feeling of hunger that is not easily satisfied.
  2. Increased thirst (Polydipsia) – most likely as a result of frequent urination.
  3. Frequent urination (Polyuria) – result  from increased renal activity as kidneys need to filter out excess sugar in the blood.

Furthermore, diabetes also comes with other symptoms such as tired/fatigue, nausea, numbness and tingling of hand and feet, blurred vision, sudden weight lost, sexual problem and slow healing of wound.

Complications of diabetes

Complications of diabetes are the most worrying part in diabetes as the symptoms will develop gradually. Over time, uncontrolled blood glucose level results in the higher risk to get the complications. Eventually, it may disable and even life threatening.  

  1. Nerve Damage (Diabetic neuropathy) – High blood sugar can injure the wall of tiny blood capillaries that nourish your nerves throughout your body. It can cause pain, numbness, burning or tingling sensation, especially on your legs. When one nerve is damaged, it is gradually spread to multiple neurons.  Thus cause alteration of functional organ in body can result in problem such as nausea, vomiting, constipation or diarrhea. For men, glucose damage the nerve which blood supply to penis, thus cause erectile dysfunction.
  • Kidney Damage (Diabetic Nephropathy)- Diabetes can damage your kidney due to kidney need to consistently wash away the glucose in your bloodstreams. The damaged kidney become leaky and let protein enter to your urine. It can progress to irreversible end-stage kidney diseases or kidney failure. This may require dialysis or kidney transplant on later stage.
  • Eye Damage (Diabetic Retinopathy)- Diabetes damage the small capillaries in your retina, cause it to break down (hemorrhage), which potentially cause vision loss or blindness. It also increases risk of developing other eyes problem such as glaucoma and cataracts. 
  • Cardiovascular disease – if you have diabetes, you are more risk to heart disease, including chest pain (angina), heart attack and narrowing of arteries (arteriosclerosis) and even stroke.  
  • Diabetic foot– Nerve damage to feet increases various foot complications. Infection from cuts and blister often occur due to poor wound healing. Diabetes may cause you more susceptible to skin problem, which will worsen the condition. Left untreated, this infection may require amputations.

Lifestyle Modification

  1. Low GI ( Glycemic Index) food– The amount and type of carbohydrate consumed will affect the blood glucose level after meals. We can plan a meal with low GI food. GI tells us a how quickly a food raise our blood glucose. GI is ranged from 0 to 100, tested by pure glucose. GI with less than 55 is considered low and it is useful to help manage glucose level. Some diabetic nutritional drink can be used as a meal replacement for diabetic individual. Other than that, good sources of carbohydrate include fruits, vegetables, whole grains, legumes can be added. Increase fiber intake and whole grain food helps in increasing insulin sensitivity and thus overcome insulin resistance. You should also get good vitamins and minerals from healthy and balance diet.
  • Artificial Sweetener– Diabetic individual should limit or avoid sugar sweetened beverages. It is a good start to swap sugary drink, energy drink, fruit juice into water, plain milk, tea and coffee. You may always try out low or zero-calories artificial sweetener as substitutes to control your blood glucose level. 
  • Cut down alcohol intake– Alcohol is high in calories that will spike up your glucose level.  It should be limited to1 drink per day (women) and less than 2 drink per day (men).
  • Eat less salt and processed food – Salt and processed food can increase risk of hypertension, which later leads to cardiovascular disease. Sodium intake should be less than 1 teaspoon per day. You can change your diet to omega-3 rich fatty acid food. EPA and DHA have beneficial effect on preventing heart disease.
  • Quit smoking– Smoker are likely to develop diabetes compare to non-smoker. Nicotine replacement therapy can be considered to make it easier to quit. The faster you quit, the faster the body start to heal.
  • Exercise regularly– being more physically active help to control your diabetes. When our muscles work, they take in glucose from the blood, liver and muscle. It improves cardiovascular risk, improve muscle strength, and contribute to weight loss.
  • Weight Management– You should be able to find out your Body Mass Index (BMI). Body Mass Index is a simple calculation using a person’s height and weight. The formula is BMI = kg/m2 where kg is a person’s weight in kilograms and m2 is their height in metres squared. A BMI of 25.0 or more is overweight, while the healthy range is 18.5 to 24.9. BMI applies to most adults 18-65 years. In addition to BMI, other physical measurements, such as body fat percentage, distribution of body fat and waist circumference, are important methods of assessing overweight and obesity. Modest weight loss of 10% over 6 months may improve glucose level responds.
  • Foot care – People with diabetes are prone to have skin infections, including bacterial and fungal infection. Performing daily foot inspection and care is very important in avoiding serious foot complications. It is also necessary to perform regular checking of wound or infection that does not heal. With proper foot care, it is estimated that as half of the foot and leg amputation can be prevented.

References

  1. American Diabetes Association. (n.d.). Understanding A1C: Diagnosis. https://www.diabetes.org/a1c/diagnosis
  2. Carbohydrates and the glycaemic index. (2020, March 16). Betterhealth. Retrieved July 24, 2021, from https://www.betterhealth.vic.gov.au/health/healthyliving/carbohydrates-and-the-glycaemic-index#bhc-content
  3. Diabetes Mellitus. (n.d.). MIMS. Retrieved July 24, 2021, from https://specialty.mims.com/diabetes%20mellitus/patient%20education
  4. Diabetes Signs. (2019, January 15). Diabetes.co.uk. Retrieved July 23, 2021, from https://www.diabetes.co.uk/The-big-three-diabetes-signs-and-symptoms.html
  5. Diabetes. (2020, October 30). Mayoclinic. Retrieved July 23, 2021, from https://www.mayoclinic.org/diseases-conditions/diabetes/symptoms-causes/syc-20371444
  6. Dionardo, M. J. (2021, May 15). 6 Lifestyle Changes to Control Your Diabetes. WebMD. https://www.webmd.com/diabetes/diabetes-lifestyle-tips
  7. Ministry of Health Malaysia. (2020). Clinical practice guidelines: Management Of Type 2 Diabetes Mellitus (6th ed.). Retrieved from https://www.moh.gov.my/

Breast Cancer





What is breast cancer
Breast cancer is the most common type of cancer affecting women in Malaysia. Among 19 women in Malaysia, there is 1 woman are at risk, compared to one in eight in Europe and the United States.

What are the symptoms of breast cancer?

Breast Cancer – Causes, Symptoms & Treatment | Gleneagles Hospital
  • A lump that is painless and hard in the breast
  • A lump at the underarm area
  • Swelling and redness of breast
  • Nipple pain, tenderness or discharge, including bleeding
  • Itchiness, soreness or rashes on nipple

How to lower the chances of breast cancer?

  • Limit the consumption of alcohol to one per day for women, two for men.
  • Do not smoke.
  • Be physically active and exercise 1.5 to 2.5 hours weekly.
  • Breastfeed your baby.
  • Maintain normal body weight and reduce high-fat diet.
  • Avoid staying up late frequently.
  • Having clinical breast exam (CBE) starting from 20s.
  • Having annual screening mammograms starting from 40 years old.
  • Talk with your healthcare providers if you are on hormone replacement therapy.
  • Self-examination

What is the diagnosis for breast cancer?

  1. Mamogram

mammogram is an X-ray for breast. It is the best way to find out breast cancer at early stage.

  • Clinical Breast Exam (CBE)

This is an examination done by a doctor or nurse, who uses his or her hands to feel for lumps or other changes.

  • Ultrasound

Ultrasound is done when a suspicious lumps are detected on your breast through breast self examination or mammogram.

  • MRI

MRI can help the healthcare providers to differentiate between normal and diseased tissue.

  • Biopsy

Biopsy diagnostic procedure that can be determine if the suspicious area is cancerous.

Any treatment can be done for breast cancer?

Breast Cancer Management - Breast Cancer Welfare Association
  1. Surgery    

There are 2 types of surgery: breast-conserving surgery and mastectomy.

Both types of surgery are often followed by radiation therapy or other treatments such as chemotherapyor hormone therapy.

  1. Radiotherapy  

Radiation therapy uses high-energy rays to kill cancer cells. 

           Common side effects of radiation therapy are:

  • Swelling and heaviness in the breast
  • Sunburn sensation at treated area
  • Fatigue
  1. Hormone therapy  

      Hormone therapy uses drugs that may either block the hormones (estrogen and progesterone) from reaching the cancer or lower the level of hormones in the body.

      Tamoxifen is an example of a hormone therapy.

     Common side effects of hormone therapy are:

  • Fatigue
  • Hot flashes
  • Vaginal discharge or irritation
  • Nausea and diarrhea
  • Weight gain
  • Changes in menstruation
  • Bone and joint pain
  1. Chemotherapy

Chemotherapy uses drugs to target cancer cells. The drugs will be injected

into the bloodstream through an intravenous (IV) needle that is inserted into a vein or through oral consumption.

Common side effects of chemotherapy are:

  • Fatigue
  • Loss of appetite
  • Nausea and/or vomiting
  • Diarrhea or constipation
  • Weight change
  • Mouth sores
  • Short-term hair loss
  • Increase the risk of infections or bleeding


Myths of breast cancer:

  1. You have breast cancer if you found out there is a lump in your breast.

Actually, only small percentage of lumps will turn out to be cancer cells. However, you can seek for medical advice from doctor if you found any persistent lump in your breast.

  • You are most likely to have breast cancer if you have a family history of breast cancer.

The truth is women who have a family history of breast cancer are in a higher risk group, but most women who have breast cancer have no family history. Statistic shows that only about 10% of individuals diagnosed with breast cancer have a family history of this disease.  

  • Mammogram can cause the spreading of breast cancer.

The harmfulness of radiation from mammogram is extremely low, it won’t cause any spreading of cancer cells.

Reference:

  1. https://www.health.ny.gov/diseases/cancer/breast/freq_asked_quest_breast_cancer.htm
  2. https://www.nationalbreastcancer.org/breast-cancer-myths/a-mammogram-can-cause-breast-cancer-to-spread/
  3. https://www.breastcancerfoundation.org.my/about-breast-cancer#how-breast-cancer-spreads
  4. https://www.cdc.gov/cancer/breast/basic_info/screening.htm

TUBERCULOSIS (TB)

What is tuberculosis?


Tuberculosis (TB) is caused by bacteria (Mycobacterium tuberculosis) that most often affect the lungs. Tuberculosis is curable and preventable.

TB is spread from person to person through the air. When people with lung TB cough, sneeze or spit, they propel the TB germs into the air. A person needs to inhale only a few of these germs to become infected.

What are the symptoms of tuberculosis?

  • A bad cough that lasts 3 weeks or longer
  • Weight loss
  • Loss of appetite
  • Coughing up blood or mucus
  • Weakness or fatigue
  • Fever
  • Night sweats
  • Chills

How is tuberculosis treated?

People diagnosed with active TB disease generally have to take a combination of medications for 6 to 8 months. The full treatment course must be completed. Otherwise, it’s highly likely a TB infection could come back. Additionally, by taking the drugs incorrectly, TB germs that are still alive may become drug-resistant, making it harder for you to get better next time.

While you are in treatment for active TB disease, you will need regular checkups to make sure your treatment is working. Everyone is different, but there are side effects associated with taking the medications, including:

  • Upset stomach, nausea and vomiting or loss of appetite
  • Tingling or numbness in the hands or feet
  • Itchy skin, rashes or bruising
  • Changes in your eyesight or blurred visions
  • Yellowish skin or eyes
  • Dark-colored urine
  • Weakness, fatigue or fever that for three or more days

Directly Observed Therapy (DOT) is the most common treatment strategy used in Malaysia. This strategy is very helpful to monitor patients’ adherence to TB therapy where a health care worker or trained lay people. TB can be controlled and cured effectively by improving the adherence of patient to TB medications.

How to prevent spread of tuberculosis to others?

  • Take your medicine exactly as the healthcare provider directed.
  • Always get your mouth cover when you cough or sneeze with a tissue. Seal the tissue in a plastic bag before throw it away.
  • Wash your hands frequently especially after sneezing or coughing.
  • Keep good ventilation in your house.
  • Do not go to work or school until your healthcare provider says it’s okay.
  • Avoid close contact with anyone. Sleep in a bedroom alone.
  • Avoid using public transportation.
  • Don’t around infants, children or people who have weak immune system.


The best vitamins for tuberculosis patient

Vitamin D

As we all know, Vitamin D3 is important for maintaining calcium homeostasis and bone mineral density. We can obtain Vitamin D through diet or exposure of epidermis to sunlight. High doses of Vitamin D supplementation enhanced clinical and radiographic improvement in TB patients were proved and concluded in a previous study. In fact, Vitamin D is also having immunomodulating role in our body. If you’re deficient in Vitamin D3, you’re very susceptible to getting an infection from either a virus or bacteria. Besides, it acts as immunosuppressant to control inflammation in TB patient. Thus, it can speed up the recovery and lessen the signs and symptoms of TB.

Vitamin C

Vitamin C is an essential micronutrient for human beings and has to be taken as dietary supplement since humans can’t synthesize Vitamin C in our body ourselves. Vitamin C protects the host from reactive oxygen and reactive nitrogen generated during mycobacterial infection. It also enhances the T-cell response and directs the increased migration of leukocytes at the infection site. There are several studies have suggested the role of Vitamin C in prevention and treatment of TB by orally administering the vitamin.


AUTISME

Apa itu autisme? Autisme adalah masalah perkembangan kompleks. Ia berlaku kepada kanak-kanak di antara 1 dalam 68 orang. Kanak-kanak lelaki mempunyai kemungkinan mendapat autism 4 kali lebih berbanding kanak-kanak perempuan.

Autisme mempengaruhi perkembangan otak dan memberi kesan kepada keupayaan individu untuk berkomunikasi, berinteraksi secara sosial dan belajar seperti kanak-kanak normal yang lain.

Simptom Autisme

Kesusahan untuk berinteraksi dan berkomunikasi secara sosial.

1. Kesukaran dalam emosi-sosial secara dua hala: Anak tersebut mungkin tidak dapat mempunyai perbualan secara dua hala, tidak menunjukkan minat kepada orang lain, ataupun tidak memulakan atau memberi respon kepada interaksi sosial seperti bercakap “hai” atau mengajak kawan lain untuk bermain.

2. Kesukaran dalam komunikasi tidak verbal: Anak ini mungkin menunjukkan gejala hubungan mata yang sangat rendah dengan orang lain, mungkin menghadapi kesukaran dalam menunjukkan gerak geri atau tidak dapat mengikut gerak geri orang dewasa seperti orang dewasa menunjuk kearah sesuatu.

3. Tidak memberi respons apabila nama dipanggil. Kerana mereka tidak memberikan tumpuan semasa dipanggil atau tiada konteks mata dan keinginan untuk berkomunikasi kerana lebih memilih untuk bermain sendirian sahaja.

Tingkah Laku Yang Terhad Atau Berulang

1. Pergerakan, penggunaan objek atau percakapan yang berulang. Anak ini mungkin mengulangi pergerakan motor dan aksi berulang kali, seperti mengepakkan tangan, berpusing atau melompat, mengulangi perkataan atau ayat yang sama, atau mungkin berinteraksi dengan permainan berulang seperti menyusun mainan atau memusingkan objek secara berterusan.

2. Minat yang sama dan terhad kepada sesuatu perkara sahaja. Anak ini mungkin menunjukkan ikatan yang kuat kepada minat tertentu seperti karakter kartun, permainan dan topik yang tertentu.

3. Hiper- atau hipo-reaktiviti terhadap penerimaan sensori. Anak ini mungkin tidak mengendahkan sensitiviti terhadap cahaya, bunyi, kesakitan, suhu, tekstur dan pergerakan dalam persekitaran mereka. Misalnya, mereka sangat seronok untuk melompat dan merempuh barang, mencari atau mengelak cahaya terang dan bunyi yang kuat, sama seperti kemahuan untuk menyentuh, menghidu atau menjilat sesuatu objek.

Komplikasi

Seseorang yang menghidap autisme akan mendapat gejala yang berlainan mengikut umur masing-masing.

  • Peringkat awal kanak-kanak – Hiperaktif, panas baran
  • Peringkat akhir kanak-kanak – suka menyerang, mencederakan diri sendiri
  • Peringkat remaja dan dewasa – kemurungan dan epilepsi

Rawatan

Standard emas untuk rawatan autisme adalah Rawatan Tingkah Laku Intensif menggunakan pendekatan Analisis Tingkah Laku Gunaan ( Applied Behavioral Analysis ABA)

Tiada ubat yang dapat menyembuhkan autisme tetapi ada beberapa jenis ubat yang dapat mengawal gejala-gejala yang timbul disebabkan autisme seperti:

  • Berkelakuan ganas
  • Hiperaktif
  • Masalah tidak mampu fokus
  • Kebimbangan yang mungkin timbul

Pemantauan Perkembangan Awal Kanak-Kanak

Sila dapatkan nasihat dari pihak profesional jika anak anda terlepas salah satu perkembangan di bawah:

4 Bulan

Memberi pandangan tepat
Mula membuat bunyi
Tersenyum apabila melihat orang lain

6 Bulan

Memberi respons apabila nama dipanggil
Mula membuat bunyi ”ah”, ”eh”, ”oh”
Boleh berguling dari posisi baring ke meniarap

9 Bulan

Memahami perkataan ”tidak”
Duduk tanpa sokongan
Boleh menggunakan jari untuk tunjuk kemahuan

12 Bulan

Berjalan dengan sokongan
Mempunyai 1 hingga 3 perkataan
Boleh menggelengkan kepala untuk nyatakan ”tidak” dan melambaikan ”bye”.

Migraine And Headache

A report done by the World Health Organization (WHO) examined more than 55,000 confirmed cases of COVID-19 and found out that headache occurred in 13.6% of the COVID-19 cases. However, the actual occurrence of headache in COVID-19 may be higher in some populations.[1] Besides that, a recent online survey explored the real-world impact of COVID-19 on patients with migraine and showed that about 60% of respondents had an increased episodes of migraine frequency, 16% reported a decrease in migraine frequency, and a little over 10% reported converting from episodic migraine to chronic migraine. [2]

Headache is one of potential symptoms of COVID -19 and it is a common condition that causes pain and discomfort in the head, neck or scalp.[1] However, migraine is often described as recurrent throbbing or pulsating, moderate or severe headache felt on either right or left side of the head.[3]

Headaches are classified into primary and secondary headaches. Primary headaches are the results of underlying process of brain whereas secondary headaches are usually due to underlying medical condition. Examples of primary headaches include tension headache, cluster headache, migraine etc.[1] There are 3 types of migraines such as migraine with aura, migraine without aura and silent migraine. Migraine without aura is the most common type, where the migraine happens without any specific warning signs.[3]


Image 1 : Tension headache, cluster headache and migraine[7]

The exact cause of migraine is unknown but the attacks from migraine are believed as the result of abnormal brain activity temporarily affecting nerve chemicals, blood vessels and signals in the brain. Migraine is initiated by specific triggers like emotional trigger, physical trigger, environmental trigger and dietary trigger as shown in the table 1 below.[3]

Specific triggerExamples
      Emotional triggerHormonal changes (3 days before and after period)
Stress
Depression
Anxiety
Excitement
Shock
        Physical triggerWorking shift Poor-quality sleep (lack of sleep)
Fatigue
Jet lag
Extreme exercise
Low blood sugar
Poor posture Neck or shoulder tension
      Dietary triggerDehydration Delayed or irregular meals Caffeine products Alcohol Specific foods; chocolate and citrus fruitTyramine based foods (cured meats, yeast extracts, smoked fish, pickles herrings and certain cheese)
    Environmental triggerBright lightsLoud noisesChanges in climate (very cold temperature)A stuffy atmosphereStrong smells

Table 1 : List of examples of specific triggers that initiate migraine[3]

There are a few treatments to reduce symptoms of migraine but there is no cure for migraine. The most common classes of drugs prescribed by healthcare professionals to treat headaches include painkillers, analgesics and anti-emetics.[4]

Prevention is better than cure. One of the best ways to prevent headaches or migraines is by avoiding the specific triggers that could possibly trigger an attack. Avoid excess caffeine intake by limiting caffeine to 2 to 3cups, or none of coffee daily can actually help in reducing migraines.[5] Staying in a quiet, dark room may help to ease migraines too. Furthermore, practising a healthy lifestyle such as sufficient sleep, lower stress, stay hydrated and exercise regularly is important to prevent migraines.

Taking supplements and herbs are also highlighted in reducing headaches and migraines. 

According to studies by University of Minnesota, taking 200mg of vitamins B12 twice daily and taking 200mg of Magnesium twice daily may help in migraine. In addition, frequency of headache may be reduced by taking150mg of coenzyme Q10 once daily.[5] Taking 60mg-100mg of Ginkgo biloba once daily also aids in reducing headaches and migraines.[6]

Conclusion

Most headaches aren’t symptoms of life-threatening medical conditions. However, please consult the doctor if you have headache for quite some time or headache that happens after any head trauma incidents.

References :

  1. https://www.healthline.com/health/headache/coronavirus-migraines (medically reviewed by Deena Kuruvilla, MD, written by Jill Seladi-Schulman, Ph.D. on 27Aug2020)
  2. https://www.medscape.com/viewarticle/950452 (by Deena Kuruvilla, MD on 12 May 2021)
  3. https://www.nhs.uk/conditions/migraine/
  4. https://www.who.int/news-room/fact-sheets/detail/headache-disorders (WHO website 8 Apr 2016)
  5. https://www.healthline.com/health/headache (medically reviewed by Saurabh Sethi, M.D., written by Rachel Nall, MSN, CRNA and Matthew Solan and Verneda Lights on 2 Aug 2018)
  6. https://pubmed.ncbi.nlm.nih.gov/19415441/ (by Giovanni D’Andrea et al. Neuro Sci. 2009 May)
  7. Image :  https://www.wisemedical.com.au/headache-or-migraine/ (website)

Amalan Pemakanan Yang Sihat Di Bulan Puasa

Puasa Ramadan ertinya menahan diri daripada makan dan minum serta segala perbuatan yang boleh membatalkan puasa, mulai dari terbit fajar sehinggalah terbenam matahari pada bulan Ramadan.


Pada bulan Ramadan, umat Islam akan menahan lapar dan dahaga lebih daripada 12 jam sehari. Oleh itu, mereka yang berpuasa perlu menggunakan dua waktu makan yang dibenarkan sehari iaitu sahur dan iftar dengan sebaik mungkin.

Penghidratan adalah salah satu risiko yang dihadapi semasa berpuasa kerana cuaca yang panas dan lembap. Ramai yang mengalami sakit kepala dan masalah untuk menumpukan perhatian semasa berpuasa. Tabiat pemakanan yang berbeza dalam 30 hari berpuasa boleh mengakibatkan pelbagai masalah penghadaman, sakti gastrik dan sembelit. Ketidakhadaman juga boleh berlaku akibat makan terlalu banyak daripada biasa semasa berbuka.

Namun begitu, daripada menambahkan jumlah makanan semasa berbuka atau sahur, lebih baik bagi anda memilih jenis dan kualiti makanan yang sesuai dimakan supaya kesan-kesan negatif berpuasa di bulan Ramadan boleh dielakkan.
Mari lihat jenis makanan yang sesuai dimakan sewaktu sahur dan berbuka untuk meningkatkan tenaga anda.


1) Kekalkan Hidrasi dengan Makanan yang Mempunyai Kandungan Air yang Tinggi

Selain daripada minum air kosong, anda boleh mengambil makanan yang tinggi dengan kandungan air seperti tembikai merah, timun, tomato dan strawberi.
Elakkan minuman yang mengandungi kafein seperti kopi dan teh kerana kafein boleh menambah pembuangan air kencing dan menyebabkan air dalam badan kita kurang.


2) Makanan Tinggi Protein

Makanan tinggi protein boleh membantu anda kurang penat sepanjang hari. Protein mengambil masa lebih lama untuk hadam dan anda akan merasa kenyang untuk tempoh masa yang panjang. Telur, keju, ayam dan daging adalah pilihan yang baik.
Susu tepung seperti MK Nutrasure dan Ensure Gold Liquid sesuai untuk diambil semasa bulan puasa kerana kandungan protein yang lebih tinggi berbanding susu tepung yang lain.


3) Makanan yang Tinggi Kandungan Kanji dan Serat

Makanan berserat tinggi boleh membantu mengawal ketidakhadaman dan pedih ulu hati. Anda boleh cuba oat, bijirin tinggi serat dan roti gandum penuh kerana ia boleh membantu anda merasa kenyang untuk tempoh masa yang lebih panjang.
Karbohidrat kompleks dalam makanan berkanji seperti nasi perang, dan kentang adalah pilihan yang bagus untuk tenaga dan mampu meningkatkan tumpuan. 

4) Penghadaman yang Lancar dengan Buah-buahan dan Sayur-sayuran

Untuk mengatasi masalah sembelit, kurangkan pengambilan makanan yang berlemak, bergoreng dan pedas sewaktu sahur. Anda boleh meningkatkan pengambilan buah-buahan dan sayur-sayuran kerana ia kaya dengan serat dan boleh mengelakkan sembelit. Amalkan brokoli, sayur bayam, keledek, lentil dalam pemakanan.


5) Pilih Lemak dan Minyak yang Sesuai

Lemak yang baik memainkan peranan yang penting dalam diet seimbang. Makanan yang kaya dengan lemak sihat seperti salmon, zaitun dan kacang-kacang boleh dirangkumi dalam pemakanan anda. Selain itu, minyak yang digunakan untuk memasak juga sangat penting. Anda boleh menggunakan minyak kepala dara, minyak dedak beras dan lain-lain.


6) Berbuka Puasa dengan Kurma

Kurma secara tradisinya dimakan pada permulaan iftar kerana ia mengandungi gula semula jadi, serat dan mineral. Selain itu, kurma mudah dicerna, menjadikannya sumber tenaga dan nutrien yang cepat bagi individu yang berpuasa.

7) Supplemen

Selain pemakanan yang sihat, supplemen dan minuman sihat adalah sumber vitamin dan mineral yang bagus.
Individu yang mempunyai masalah gastrik atau ketidakhadaman boleh mengambil probiotik untuk mengurangkan senak dan kembung yang disebabkan oleh perubahan tabiat makan secara tiba-tiba. Probiotik boleh membantu menyeimbangkan semula mikroflora normal dalam sistem pencernaan dan megurangkan risiko gastrik.

Susu tepung seperti MK Glucerwin, MK Colostrum, Ensure Gold Liquid, Glucerna membekalkan nutrisi yang lengkap dan membekalkan makro- dan micro-nutrien yang diperlukan oleh badan kita. Susu tepung adalah pilihan alternatif yang sesuai untuk Muslim yang berpuasa sebagai makanan penggantian pada waktu sahur atau iftar.

Bagi individu yang tidak gemar susu tepung atau minuman sihat, multivitamin adalah pilihan terbaik semasa bulan puasa. Multivitamin bukan hanya membekalkan vitamin dan mineral yang lengkap, ia juga membantu membekalkan tenaga untuk badan kita sepanjang tempoh
berpuasa. Oleh itu, multivitamin adalah penting pada bulan puasa untuk menambahkan balik vitamin dan mineral yang diperlukan untuk seharian.

Perlu diingatkan bahawa kesederhanaan adalah kunci untuk pemakanan sihat. Selain itu, kita juga harus mengamalkan pergerakan fizikal yang aktif, contohnya, dengan berjalan-jalan atau berjoging setiap hari. Pemakanan yang sihat adalah penting dan harus diamalkan selalu bukan sahaja pada bulan puasa! Dengan ini, kami mengucapkan selamat berpuasa kepada semua orang!

Cholesterol

        

Human heart disease and chest pain from clogged arteries and artery damaged with cholesterol resulting in a cardiac arrest with 3D illustration elements.


What is cholesterol?

Cholesterol is a type of lipid. It is a waxy, fat-like substance that liver produces naturally. It is vital for the formation of cell membranes, certain hormones (estrogen & testosterone), vitamin D and bile acid.

However, too much of cholesterol can combine with other substances in the blood to form plaque. Plaque sticks to the walls of the arteries causing atherosclerosis.  This leads to coronary artery disease, heart attack or stroke due to blockage or narrowing of the arteries.

There are two types of lipoproteins that carry cholesterol to and from cells, which are low-density lipoprotein (LDL) and high-density lipoprotein (HDL).

Types of cholesterol

  • LDL (bad) cholesterol

LDL cholesterol is considered the “bad” cholesterol, because it contributes to fatty build-ups in the arteries (atherosclerosis). This narrows the arteries and increases the risk for heart attack, stroke and peripheral artery disease.

  • HDL (good) cholesterol

HDL cholesterol can be thought of as the “good” cholesterol because a healthy level of HDL in the blood may protect us against heart attack and stroke.

HDL also carries LDL (bad) cholesterol away from the arteries and back to the liver, where the LDL will be broken down and passed out from the body. But HDL cholesterol doesn’t completely eliminate LDL cholesterol. Only one-third to one-fourth of blood cholesterol is carried by HDL.

  • Triglycerides

Triglycerides are the most common type of fat in the body. They store excess energy from your diet.

A high triglyceride level combined with high LDL (bad) cholesterol or low HDL (good) cholesterol is often linked with fatty build-up within the artery walls, which increases the risk of heart attack and stroke.

Symptoms

High cholesterol levels do not usually cause any symptoms. In most cases it only causes emergency events. For instances, angina (chest pain), high blood pressure, stroke or a soft, yellowish growths or lesions on the skin called xanthomas, fatigue, weight gain, stomach distention and aching pain.

Risk factor

  • Age
  • Overweight or obese
  • Unhealthy eating habits
  • Lack of physical activity
  • Smoking
  • Have a family history of high cholesterol
  • Have diabetes, high blood pressure

Treatment of Hypercholesterolemia

  • HMG CoA Reductase Inhibitors (Statins)

Statin lowers LDL-cholesterol level by reducing the liver’s production of cholesterol and improve liver’s ability to remove LDL-cholesterol that is already in the blood. It is the first line agent in treating hypercholesterolemia.

Statin should be taken at night. It is contraindicated in pregnancy, lactation, women of child bearing potential and liver failure patient. The most common side effects of statin are muscle aches, gastrointestinal discomfort, headache.

Examples: Simvastatin, lovastatin, atorvastatin and rosuvastatin.

  • Cholesterol Absorption Inhibitors

Cholesterol absorption inhibitors selectively blocks intestinal absorption of both dietary and biliary cholesterols and other phytosterols thus reducing the amount of cholesterol that travel from intestine to liver, lowering the amount of cholesterol stored in the liver and hence increasing the amount of cholesterol that can be cleared from the blood.

It can be used in combination with any dose of any statin to further lowering LDL-C if targets are not achieved. Besides, it may be considered as monotherapy in patients who cannot tolerate statins.

There is no major adverse effects have been reported. The most frequent adverse effects are stomachache, diarrhea, headache, fatigue, muscle aches.

Example: Ezetimibe

  • Fibric Acid Derivatives (Fibrates)

Fibrates are Peroxisome Proliferator Activated Receptor (PPAR) – α agonist which have an important role in fatty acid oxidation. They reduce serum TG effectively and increase HDL-C modestly. It is limited to the treatment in patient with very high TG levels.

Common side effects are gastrointestinal discomfort, flushing of the skin, dizziness, headache.

Example: fenofibrate (take with meal and swallow whole with water), gemfibrozil (take 30mins before meal)

  • PCSK9 Inhibitors

PCSK9 inhibitors are a new class of drugs that lower LDL. It works by inhibiting the binding of PCSK9 to the LDL-receptors. Currently, it is only available as an injection administered subcutaneously at 2-4 weeks intervals. Common side effects are injection-site swelling, flu-like symptoms, nausea and joint pains.

Example: evolocumab, alirocumab

Nutritional Supplements for High Triglycerides and Cholesterol

  • Red yeast rice

Red yeast rice is a type of fermented rice. It contains monacolin k, a naturally substance that is similar to lovastatin. Thus, it is able to lower the cholesterol. Studies show that it is able to reduce 22% of cholesterol after about 8weeks of consuming it.

  • Fish oil

Fish oil is polyunsaturated fatty acids (PUFA) that only comes from food like herring, mackerel, salmon etc. It is available in liquid or soft gel form. Omega-3 fatty acid in fish oil is able to reduce triglycerides level, prevent the formation of harmful blood clots and improve heart health.

  • Oat beta glucan

It is a soluble dietary fibre that will form viscous gel in the stomach before entering the intestines. The gel will then attach to bile acid and remove them from the body. Body will then use more cholesterol to reproduce bile thereby reducing cholesterol in the body.

  • Flaxseed oil

Flaxseed oil contains alpha linoleic acid (ALA), a form of omega 3 fatty acids that is found in walnut, flaxseed and chiaseed. It is used to lower the cholesterol level by reducing the LDL-C. Flaxseed oil is available in liquid or softgel form. It is suitable for vegetarian.

  • Lecithin

Lecithin is a type of fat that can be found naturally in many foods that’s essential to human health. Most lecithin supplements are made from soybeans. Phosphatidylcholine, a major component of lecithin is responsible for lecithin’s reported health benefits. It is able to reduce LDL and may also raise the level of  HDL.

  • Coenzyme Q10 (CoQ10)

CoQ10 is an antioxidant naturally produced by the body that is essential for cellular energy production in mitochondria by converting food into energy. It aids in lowering cholesterol and improving heart health. Cholesterol-lowering statin drugs can reduce CoQ10 production in body, hence CoQ10 supplements are important to restore CoQ10 levels in the body and also to reduce statin side effects (like muscle aches).

  • Probiotics

Probiotics are groups of beneficial bacteria that our body needed for good health and vitality. Probiotics,  particularly Lactobacilli plantarum and lactobacilli reuteri can help to reduce cholesterol level by binding with the cholesterol in the intestine to stop it from being absorbed and also produce short-chain fatty acids to prevent cholesterol from being formed by the liver. Probiotics also produce bile acids that help to metabolize fat and cholesterol in the body.

Lifestyle modification

  • Have a healthy diet

Reduce the intake of saturated fats and trans fat like red meat and dairy products that are made with whole milk. Choose skim milk, low fat or fat-free dairy products instead. Limit fried food and cook with vegetable oils like sunflower oil, olive oil. Consume more leafy vegetables, fruits and whole grains. Always choose to prepare food at home and if having meals outside; choose food with that is grilled, steamed or boiled.

  • Become more physically active

A sedentary lifestyle lowers the level of HDL cholesterol. Less HDL means there’s less good cholesterol to remove bad cholesterol from the arteries. Hence, physical activity is important. It is recommended to exercise 30-45mins per session at least 5 times a week to improve cardiovascular fitness, raise HDL-C and decrease triglycerides level. Aerobic exercise like brisk walking, jogging, cycling and swimming are recommended.

  • Quit smoking

Smoking can lower HDL cholesterol. A person with unhealthy cholesterol levels who also smokes will have increased risk of coronary heart disease. By quitting, smokers not only can lower their LDL cholesterol and increase HDL cholesterol but also can help to protect their arteries.  

  • Restrict alcohol intake

Alcohol is the macronutrient that contributes to the increase in serum triglycerides. In a person with elevated serum triglycerides, excess alcohol consumption can further exacerbate hyperlipidemia. Thus, alcohol consumption should be restricted to not more than 14 units for male and 7 units for female per week. * 1unit = 250ml of beer = 100ml of wine = 30ml of whiskey

  • Weight reduction

Being overweight or obese is linked with increased level of bad cholesterol and decreased level of good cholesterol in the body. A weight loss of 5-10 % is able to enhance total cholesterol and LDL-cholesterol lowering effects, at the same time increase HDL-cholesterol. Therefore, it is important to maintain at normal bodyweight. Recommended BMI for Asians is 18.5kg/m–23kg/m2.

References

  1. Everything You Need to Know About High Cholesterol. Available from https://www.healthline.com/health/high-cholesterol
  2. Cholesterol. Available from https://medlineplus.gov/cholesterol.html
  3. HDL (Good), LDL (Bad) Cholesterol and Triglycerides. Available from https://www.heart.org/en/health-topics/cholesterol/hdl-good-ldl-bad-cholesterol-and-triglycerides
  4. Understanding Cholesterol Numbers. Available from https://www.webmd.com/cholesterol-management/guide/understanding-numbers
  5. Understanding Cholesterol Problems: Symptoms. Available from https://www.webmd.com/cholesterol-management/guide/understanding-cholesterol-problems-symptoms
  6. High Cholesterol Risk Factors. https://www.webmd.com/cholesterol-management/high-cholesterol-risk-factors
  7. 5th edition of clinical practice guideline : Management of dyslipidemia 2017.
  8. Thu Nguyen, Mitchell Karl and Antonello Santini (2017) : Red yeast Rice
  9. Yuka Kawakami, Hisami Yamanaka-Okumura, Yuko Naniwa-Kuroki, Masae Sakuma, Yutaka Taketani & Eiji Takeda (2015) : Flaxseed oil intake reduces serum small dense low-density lipoprotein concentrations in Japanese men: a randomized, double blind, crossover study
  10. Amouni Mohamed Mourad, Eder de Carvalho Pincinato, Priscila Gava Mazzola, Maricene Sabha, Patricia Moriel, “Influence of Soy Lecithin Administration on Hypercholesterolemia”, Cholesterol, vol. 2010, Article ID 824813, 4 pages, 2010.
  11. Robertson R. Do Probiotics Benefit Heart Health? [Internet]. Healthline. 2018 [cited 18 October 2021]. Available from: https://www.healthline.com/nutrition/probiotics-and-heart-health
  12. Prevention and Treatment of High Cholesterol (Hyperlipidemia) [Internet]. www.heart.org. 2020 [cited 18 October 2021]. Available from: https://www.heart.org/en/health-topics/cholesterol/prevention-and-treatment-of-high-cholesterol-hyperlipidemia

Penyakit Asma (Asthma)

Apakah itu asma?

Asma merupakan penyakit paru-paru kronik yang membengkak dan menyempitkan saluran pernafasan. Semasa serangan asma, simptom-simptom yang mungkin akan pesakit mengalami adalah seperti ‘wheezing’ (bunyi bersiul apabila sedang bernafas), kesesakan dada, sesak nafas dan batuk.

Serangan yang ringan hanya akan berlangsung selama beberapa minit dan dapat diselesaikan sama ada secara spontan ataupun dengan ubat sedutan pelega. Serangan yang teruk akan berterusan walaupun dengan penggunaan ubat sedutan, dan akan memerlukan pemeriksaan segera oleh doctor.


Apakah Penyebab Asma?

Faktor-faktor ini berbeza untuk setiap individu:

  1. Jangkitan sistem pernafasan seperti selesema, sinusitis dan bronkitis
  2. Pencemaran udara ataupun pendedahan kepada asap rokok
  3. Bahan penyebab alahan seperti debu, bulu haiwan, makanan, dan lipas
  4. Pendedahan kepada cuaca sejuk dan kering atau perubahan suhu secara tiba-tiba
  5. Perubahan emosi atau tekanan
  6. Senaman fizikal
  7. Ubat-ubatan (aspirin, asid mefenamic, ibuprofen)

Apakah Gejala Asma?

Serangan asma mungkin berlaku secara tiba-tiba atau secara progresif selama beberapa hari atau jam. Simptom yang menandakan serangan asma adalah seperti berikut:

  1. Bunyi berdeham atau “wheezing” semasa bernafas
  2. Sesak nafas
  3. Ketat dada
  4. Batuk
  5. Kesukaran bercakap
  6. Keletihan
  7. Jantung berdebar-debar
  8. Penggunaan otot aksesori untuk bernafas
  9. Kadar pernafasan berkurang

Apakah Rawatan Asma?

Ubat-Ubatan

1. Ubat Penyelamat (reliever)

Ubat penyelamat diambil apabila tanda-tanda serangan asma bermula. Contoh: Salbutamol.

2. Ubat Pengawal (controller)

Ubat pengawal diambil setiap hari untuk kawalan asma yang berterusan. Ia membantu mengurangkan keradangan ketika serangan asma.
Contoh: Budesonide, Fluticasone.

Supplemen

1. Vitamin D

Vitamin D dianggap memberi kesan kepada tahap sel imun tertentu dan mengurangkan tindak balas keradangan yang disebabkan oleh jangkitan pernafasan virus. Banyak kajian telah menunjukkan hubungan antara vitamin D dan asma. Tahap vitamin D yang tinggi telah dijumpai untuk melindungi daripada perkembangan asma dan wheeze yang berulang pada zaman kanak-kanak. 

2. Vitamin C

Vitamin C mempunyai ciri-ciri anti-radang dan antioksidan yang menjadikan ia potensi minat dalam asma.

Antioksidan biasanya menghalang kesan merosakkan tekanan oksidatif dan spesies oksigen reaktif yang dihasilkan oleh sel-sel radang di dalam paru-paru. Idea ini ialah pengambilan antioksida yang rendah seperti vitamin C menyebabkan ketidakseimbangan yang menyokong keradangan kronik dan kerosakan pada paru-paru.

3. Cendawan susu harimau (Tigermilk Mushroom)

Cendawan susu harimau merupakan salah satu alternative yang boleh menguatkan system pernafasan. Cendawan susu harimau boleh melegakan simptom pernafasan contohnya batuk kronik dan berulang, asma dan resdung dengan berkesan sebab ia merupakan agen anti radang yang semula jadi.

4. Cordyceps Sinesis

Cordyceps mengandungi nutrient seperti adenosine, cordycepin, asid cordycepic, polisakarida, asid amino dan vitamin. Menurut klinikal studi, Cordyceps dapat meredakan masalah pernafasan seperti asma atau batuk dan menguatkan fungsi paru-paru.

5. Bawang Putih

Bawang putih mengandungi bahan pencegah radang (anti-inflammatory) dan juga allicin iaitu sejenis agen antioksida yang dapat mengurangkan serangan asma.

Langkah-langkah untuk mencegah serangan asma

1. Hindari daripada allergen
Allergen seperti bulu binatang, debu, serbuk dari bunga harus dielakkan.

2. Hindari daripada asap rokok
Asap rokok dapat mengiritasi saluran penafasan dan seterusnya mengalami serangan asma. Oleh itu pesakit asma digalakkan berhenti rokok suaya melindungi paru-paru sendiri.

3. Rajin olahraga
Berolahraga dapat membantu melatih stamina otot pernafasan dan memperkuat daya tahan tubuh penderita asma. Berenang agak digalakkan oleh doctor untuk penderita asma. Elakkan berolahraga ketika cuaca dingin ataupun cuaca jerebu.

4. Laraskan diet
Gastritis atau GERD merupakan salah satu factor risiko asma. Oleh itu, laraskan diet agar acid perut tidak naik dan mencetuskan asma. Elakkan kopi, the, makanan pedas dan masam.

5. Vaksinasi Flu
Influenza akan menyebabkan masalah paru-paru yang sedia ada menjadi lebih teruk. Pesakit asma digalakkan mengambil vaksin supaya mendapat perlindungan yang lebih baik terhadap pesakit asma.

Cara penggunaan inhaler (MDI) yang betul

  1. Duduk atau berdiri tegak
  2. Keluarkan penutup dari corong
  3. Letakkan alat sedut dengan jari telunjuk di bahagian atas tabung dan ibu jari di bahagian bawah
  4. Goncang alat sedut
  5. Tarik nafas sepenuhnya melalui mulut dan hembus nafas perlahan-lahan
  6. Letakkan pelekap mulut alat sedut di dalam mulut. Tutup bibir di sekitar corong dengan rapat. Dongakkan kepala sedikit ke belakang
  7. Mula untuk menarik nafas perlahan-lahan dan mendalam melalui corong dan pada masa yang sama tekan ke bawah pada tabung alat sedut dengan jari telunjuk
  8. Terus tarik nafas dalam dan dengan perlahan-lahan tahan nafas selama 5 hingga 10 saat (mengikut kemampuan)
  9. Keluarkan alat sedut dari mulut dan hembus nafas perlahan-lahan melalui hidung tanpa membuka mulut
  10. Tunggu 1 minit sebelum mengulangi dos kedua
  11. Gantikan penutup selepas digunakan
  12. Bilas mulut selepas menggunakan steroid yang telah disedut

Benign Prostatic Hyperplasia

Benign Prostatic Hyperplasia (BPH)

Benign prostatic hyperplasia (BPH) is a condition in men where the prostate gland is enlarged but non-cancerous. As the prostate enlarges, the gland presses and pinches against the urethra. The bladder wall becomes thicker (Figure 1). Eventually, the bladder may become weaken and lose the ability to empty completely, leaving some urine in the bladder.


Figure 1: Normal prostate vs enlarged prostate

BPH affects about 50 percent of men between the ages of 51 and 60 and up to 90 percent of men older than 80, evidence clearly shows that the morbidity of BPH increase with age. In addition, BPH can be induced by a range of risk factors, including obesity, hyperlipidemia, type 2 diabetes, genetic factor and certain hormonal disorders.

The common symptoms of BPH includes:

  •  Difficulty starting to urinate despite pushing and straining
  • A weak stream of urine; several interruptions in the stream
  • Dribbling at the end of urination
  • A sudden strong desire to urinate
  • Frequent urination
  • The sensation that the bladder is not empty after urination is completed
  • Frequent awakening at night to urinate (nocturia)
  • Pain while urinating

How is benign prostatic hyperplasia (BPH) treated?

At present, the primary goals of BPH treatment are to improve quality of life, inhibit disease progression, and reduce complications. BPH is usually treated with alpha-adrenergic blockers and 5-alpha reductase inhibitors. Alpha blocker helps to relax the smooth muscles of the prostate and bladder neck to improve urine flow and reduce bladder blockage. It has faster onset of action so it is recommended as first line treatment for men with mild to moderate symptoms. Examples of alpha blockers are terazosin (Hytrin), doxazosin (Cardura) (Kamiren XL), tamsulosin (Harnal OCAS) and alfuzosin (Xatral). 5-alpha-reductase inhibitors are medicines that can stop the prostate from growing further or even cause it to shrink by decreasing the production of hormone, dihydrotestosterone (DHT) which affects the growth of prostate gland. Finasteride (Proscar) and dutasteride (Avodart) are example of alpha-reductase inhibitors.

Apart from medications, behavioural modifications and therapies may be helpful, particularly as an adjunct to medications. Lifestyle changes include nightly fluid restriction, timed bladder voiding, double-voiding techniques, regular physical activity, pelvic floor muscle training and avoiding caffeine, alcohol, and highly seasoned food.

*Double voiding – it involves passing urine twice each time you go to toilet. Firstly, urinate as usual then wait for 20-30 seconds, urinate again. This technique is effective for those who feel like their bladder is not empty or who return quickly to the bathroom after voiding.

Natural remedies for enlarged prostate (BPH)

  • Saw palmetto

Remedy that comes from fruit of palm tree. It is an inhibitor of 5 alpha reductase. It has anti-inflammatory and hormone-blocking properties. Saw palmetto is used to relieve urinary symptoms caused by benign prostatic hyperplasia (BPH).

  • Pygeum bark

It contains a wide range of fatty acids, alcohols and sterols such as beta-sitosterol. It has an antioxidant and anti-inflammatory effect on urogenital system. Able to improve symptoms of benign prostatic hyperplasia.

  • Tomato

It consists of lycopene, a powerful antioxidant that protect cells from damage and improve prostate health.

  • Pumpkin seed

It consists of zinc which is able to decrease the production of dihydrotestosterone (DHT) and inhibit this androgen from binding to receptors, potentially reducing BPH symptoms.

  • Cranberry

It contains phytonutrients with anti-inflammatory properties. It is used to prevent bladder and urinary tract infection by preventing bacteria from sticking to the wall of the bladder. Shown improvement in urinary flow.

References:

  1. Information H, Diseases U, Problems P, Hyperplasia) P, Hyperplasia) P, Health N. Prostate Enlargement (Benign Prostatic Hyperplasia) | NIDDK [Internet]. National Institute of Diabetes and Digestive and Kidney Diseases. 2021 [cited 18 October 2021]. Available from: https://www.niddk.nih.gov/health-information/urologic-diseases/prostate-problems/prostate-enlargement-benign-prostatic-hyperplasia
  2. Egan K. The Epidemiology of Benign Prostatic Hyperplasia Associated with Lower Urinary Tract Symptoms. Urologic Clinics of North America. 2016;43(3):289-297.
  3. Calogero A, Burgio G, Condorelli R, Cannarella R, La Vignera S. Epidemiology and risk factors of lower urinary tract symptoms/benign prostatic hyperplasia and erectile dysfunction. The Aging Male. 2018;22(1):12-19.
  4. Yoo S, Oh S, Park J, Cho S, Cho M, Jeong H et al. The impacts of metabolic syndrome and lifestyle on the prevalence of benign prostatic hyperplasia requiring treatment: historical cohort study of 130 454 men. BJU International. 2018;123(1):140-148.
  5. Yu Z, Yan H, Xu F, Chao H, Deng L, Xu X et al. Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia. Frontiers in Pharmacology. 2020;11.
  6. Fonseca J, Martins da silva C. The diagnosis and treatment of lower urinary tract symptoms due to benign prostatic hyperplasia with α-blockers: focus on silodosin. Clin Drug Investig. 2015;35(suppl 1):7-18.
  7. 10 natural remedies for enlarged prostate and lifestyle tips [Internet]. Medicalnewstoday.com. 2021 [cited 4 November 2021]. Available from: https://www.medicalnewstoday.com/articles/321231#lifestyle-tips

HYPERTENSION (HIGH BLOOD PRESSURE)

                                             What is Hypertension?

Hypertension is defined as persistent elevation of systolic blood pressure (BP) of 140 mmHg or greater and/or diastolic BP of 90 mmHg or greater, taken at least twice on two separate occasions.


What are the symptoms of Hypertension

Hypertension is generally a silent condition as it has no particular symptoms. However, there are some symptoms which occur simultaneously can be associated with high blood pressure. These symptoms include:

  • Headaches
  • Shortness of breath
  • Nose bleed
  • Facial redness and fatigue
  • Dizziness
  • Chest pain
  • Visual changes
  • Blood in the urine
  • Throwing up
  • Asphyxiated
  • Agitated

What are the causes of Hypertension

The exact causes of primary hypertension remains unclear, but several risk factors are strongly and independently associated with its development, which include:

1) Age
Advancing age is associated with increased blood pressure, particularly systolic blood pressure and an increased incidence of hypertension.

2) Obesity
Obesity and weight gain are major risk factors for hypertension and are also determinants of the rise in blood pressure that is commonly observed with aging.

3) Family history
Hypertension is approximately twice as common in subjects who have one or two hypertensive parents and multiple epidemiologic studies suggest that genetic factors account for approximately 30 percent of the variation in blood pressure in various populations.

4) High-sodium diet
Excess sodium intake (eg: >3 g/day [sodium chloride]) increases the risk for hypertension and sodium restriction lowers blood pressure in those with a high sodium intake.

5) Excessive alcohol consumption
Excess alcohol intake is associated with the development of hypertension and alcohol restriction lowers blood pressure in those with increased intake.

6) Physical inactivity
Physical inactivity increases the risk for hypertension and exercise is an effective means of lowering blood pressure.

What are the effects of Hypertension on the body?

The blood vessels and body organs can be damaged by the excessive pressure on the artery walls caused by hypertension. The higher the blood pressure and the longer it goes uncontrolled, the greater the damage.
Uncontrolled high blood pressure can lead to complications including:

1) Damaged arteries

Healthy arteries are flexible and strong. Blood flows freely and unobstructed through healthy arteries and vessels.
Hypertension makes arteries tougher, tighter, and less elastic. This damage makes it easier for dietary fats to deposit in your arteries and restrict blood flow. This damage can lead to increased blood pressure, blockages, and, eventually, heart attack and stroke.

2) Damaged heart

To pump blood against the higher pressure in the vessels, the heart has to work harder. This causes the walls of the heart’s pumping chamber to thicken (left ventricular hypertrophy). Eventually, the thickened muscle may have a hard time pumping enough blood to meet the body’s needs, which can lead to heart failure.

3) Damaged other organs

Weakened and narrowed blood vessels in kidneys which can prevent these organs from functioning normally.
Thickened, narrowed or torn blood vessels in the eyes. This can result in vision loss.

4) Damaged brain

Your brain relies on a healthy supply of oxygen-rich blood to work properly. High blood pressure can reduce your brain’s supply of blood.
Narrowed or blocked arteries can limit blood flow to the brain, leading to a certain type of dementia (vascular dementia). A stroke that interrupts blood flow to the brain also can cause vascular dementia.

What are the treatments of Hypertension?

MEDICATIONS

1) ACE Inhibitors
Angiotensin-converting enzyme (ACE) inhibitors reduce blood pressure by relaxing your blood vessels.
Example: Perindopril, Enalapril, Ramipril

2) Angiotensin II Antagonists
Angiotensin II antagonist work in a similar way to ACE inhibitors. They’re often recommended if ACE inhibitors cause troublesome side effects.
Example: Ibesartan, Losartan, Valsartan

3) Beta-Blockers
Beta blockers can reduce blood pressure by making your heart beat more slowly and with less force.
Example: Atenolol, Bisoprolol.

4) Calcium Channel Blockers
Calcium channel blockers reduce blood pressure by widening your blood vessels.
Example: Amlodipine, Nifedipine, Felodipine

5) Diuretics
Diuretics work by flushing excess water and salt from the body through your urine.
They’re often used if calcium channel blockers cause troublesome side effects.
Example: Furosemide, Amiloride, Spironolactone

SUPPLEMENT


1) Fish Oil
Fish oil may improve heart health by reducing blood lipid levels, inflammation, and high blood pressure. Studies show that those with high blood pressure may benefit from high-dose fish oil supplements (0.18-15g per day with 450-600mg content of EPA and DHA per g of fish oil).


2) Garlic
Garlic is found benefit in reducing both blood pressure and heart disease risk. Adding a garlic supplement may help lower blood pressure naturally. In fact, garlic supplements reduced systolic and diastolic blood pressure by an average of 8.3 mmHg and 5.5 mmHg respectively. It is estimated that this reduction may help decrease the risk of stroke, heart attack, and coronary artery disease by up to 40%.

3) CoQ10
CoQ10 is suggested to improve heart-related conditions like hypertension through neutralizing free radicals, increasing the production of energy in cells, and preventing the formation of blood clots. There is study suggest that this supplement can help in reducing both systolic and diastolic blood pressure (dose vary from 75–360 mg/day).


4) Magnesium
Magnesium is a mineral that’s critical for many bodily functions, including blood pressure regulation. Magnesium supplements may help reduce blood pressure by increasing the production of nitric oxide, a signaling molecule that helps relax blood vessels.
Every 100-mg daily increase in dietary magnesium was linked to a 5% reduction in high blood pressure risk.

Urinary Tract Infection

What is a urinary tract infection?

A urinary tract infection (also called a “UTI”) happens when bacteria get into the urinary system and multiply. This infection can happen in any part of your urinary system — your kidneys, ureters, bladder and urethra.

Urinary tract is further divided into two sections:


The upper urinary tract is composed of the kidneys and ureters. Infection in the upper urinary tract generally affects the kidneys (pyelonephritis).

The lower urinary tract consists of the bladder and the urethra. Infection in the lower urinary tract can affect the urethra (urethritis) or the bladder (cystitis).

Who are more prone to UTIs?

  • Women get UTIs much more often than men. This is because women have a shorter urethra, which may make it easier for bacteria to reach the bladder.
  • People with diabetes may have changes in their body’s defense system, making it easier to get urinary infections.
  • People with blockages in their urinary tract, such as a kidney stone, are more likely to get UTIs.
  • An enlarged prostate gland in a man can also block the flow of urine and cause a UTI.
  • People who have a catheter (tube) placed in their bladder for a long time are more prone to UTIs. This is because bacteria on the catheter can infect the bladder.
  • Couple who are sexually active. Sexual intercourse can introduce larger numbers of bacteria into the bladder.

What are the symptoms of a UTI?

Most people will have one or more of the following:

  • A burning feeling during urination
  • An urgent need to urinate, often with only a few drops of urine to pass
  • An aching feeling, pressure, or pain in the lower abdomen (stomach)
  • Strong odour of the urine
  • Cloudy or blood-tinged urine

If the infection spreads to the kidneys and becomes more serious, you may also have:

  • pain in the lower back
  • fever and chills
  • nausea and vomiting

Can anything be done to help prevent UTIs?

The following steps may help:

  • Drink plenty of fluids, 8 glasses of water a day.
  • Do not postpone going to the bathroom.  Urinate when you feel the urge.
  • Wipe from front to back to prevent bacteria from the bowels (intestines) from getting into the urinary tract.
  • Wash the genital area before and after having sex.
  • Regular change of catheter to prevent the growth of bacteria

DON’T

  • do not use scented soap/ vagina wash to prevent irritation
  • do not hold your pee in if you feel the urge to go
  • do not wear tight, synthetic underwear, such as nylon
  • do not drink lots of alcoholic drinks, as they may irritate your bladder
  • do not have lots of sugary food or drinks, as they may encourage bacteria to grow

NATURAL HOME REMEDIES FOR UTIS YOU CAN TRY RIGHT FROM HOME

  • Cranberry juice

The anthocyanidins and proanthocyanidins (PAC) are tannins found in cranberries and function as a natural defense system against microbes

  • Probiotic

probiotics may prevent harmful bacteria from attaching to the urinary tract cells, and may also lower the urine Ph, making it less hospitable to harmful bacteria.

Probiotics are found in supplement form (often a capsule), or they occur naturally in some types of food, including certain yogurts, kombucha, or kefir.

  • Eating Garlic

Allicin and other sulphur compounds are thought to be the major antimicrobial factors in garlic.

  • Adding vitamin C to your diet

Adequate amount of Vitamin C may also acidify your urine, which limits the growth of some bacteria and may prevent urinary tract infections from occurring.

  • Celery juice

Celery extract has antibacterial properties to inhibit the bacterial growth in urinary bladder

Source:

National Kidney Foundation_https://www.kidney.org/atoz/content/uti

https://www.nhs.uk/conditions/urinary-tract-infections-utis/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370320/ _doi: 10.6061/clinics/2012(06)18

Universiti Putra Malaysia (UPM). “Using garlic to combat antimicrobial resistant urinary tract infections.” ScienceDaily. ScienceDaily, 10 July 2015.

https://www.medicinenet.com/urinary_tract_infection/article.htm

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